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NCT05868486 · ClinicalTrials.gov registry record · Early Phase 1
Analysis of Whole Body Magnetic Resonance Imaging and Liquid Biopsy for Early Detection of Cancer in Patients With a Strong Family History of Cancer
A Early Phase 1 study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid System Neoplasm, sponsored by City of Hope Medical Center.
- Active
- Registry status
- Early Phase 1
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT05868486 is a Early Phase 1 study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid System Neoplasm that is active but no longer recruiting, run by City of Hope Medical Center. The registered enrollment target is 100 participants, below the 1,140-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05868486, a Early Phase 1 study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid System Neoplasm, is active but no longer recruiting, sponsored by City of Hope Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
This study evaluates patient acceptability of whole body magnetic resonance imaging (WBM) and liquid biopsies (LB) in detecting early stage cancer in patients with a strong family history of cancer. Collecting family history and testing for genes passed on from parent to child (germline testing) can be used to predict the likelihood of a patient developing cancer. Currently, detection of early cancers focuses on screening specific organ systems such as breast and colon cancer. Magnetic resonance imaging (MRI) uses a large magnet and radio waves to look at organs and structures inside the body. Health care professionals use MRI scans to diagnose a variety of conditions, from torn ligaments to cancer. Liquid biopsy is test that analyzes blood samples to determine if cancer cells are present. This study may help researchers determine the feasibility of WBM and liquid biopsies to detect early stage cancer in patients that have a strong family history of cancer.
Conditions Studied
Interventions
- PROCEDURE Biospecimen Collection
- OTHER Survey Administration
- PROCEDURE Liquid Biopsy
- GENETIC Genetic Testing for Cancer Risk
- PROCEDURE Magnetic Resonance Imaging of the Whole Body without Contrast
Study Locations (1)
California
- City of Hope Medical Center - Duarte
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2022-05-20 |
| Est. Completion | 2026-10-19 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05868486
The ClinicalTrials.gov registry entry for NCT05868486 describes a study currently listed as active not recruiting, categorized as Early Phase 1. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,140-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (91% lower). The listed sponsor is City of Hope Medical Center, which has 582 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Malignant Solid Neoplasm appearing as the primary indexed condition, and to 5 interventions - of which Biospecimen Collection is the first listed.
NCT05868486 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05868486 about?
NCT05868486 is a clinical study titled "Analysis of Whole Body Magnetic Resonance Imaging and Liquid Biopsy for Early Detection of Cancer in Patients With a Strong Family History of Cancer". This study evaluates patient acceptability of whole body magnetic resonance imaging (WBM) and liquid biopsies (LB) in detecting early stage cancer in patients with a strong family history of cancer. Collecting family history and testing for genes passed on from parent to child (germline testing) can...
What is the current status of trial NCT05868486?
This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 100 participants. The study started on 2022-05-20. Estimated completion is 2026-10-19.
What conditions does trial NCT05868486 study?
This clinical trial studies the following conditions: Malignant Solid Neoplasm, Hematopoietic and Lymphoid System Neoplasm.
What interventions are being tested in trial NCT05868486?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Survey Administration (OTHER), Liquid Biopsy (PROCEDURE), Genetic Testing for Cancer Risk (GENETIC), Magnetic Resonance Imaging of the Whole Body without Contrast (PROCEDURE).
Who is sponsoring clinical trial NCT05868486?
This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05868486 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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