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NCT05857852 · ClinicalTrials.gov registry record · NA
Low-Intensity Focused Ultrasound for Cocaine Use Disorder
A NA study, sponsored by University of Virginia.
- Completed
- Registry status
- NA
- Development phase
- 25
- Enrollment target
NCT05857852: Completed NA study, sponsored by University of Virginia.
NCT05857852 is a NA study that has completed, run by University of Virginia. The registered enrollment target is 25 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05857852, a NA study, has completed, sponsored by University of Virginia.
- COMPLETED
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
Study Summary
This study aims to understand the role of Low-Intensity Focused Ultrasound on craving levels for cocaine as evidenced by diagnostic imaging of the dorsal anterior insula (dAI) and subjective ratings. Data analysis will serve to show if 1) LIFU is safe and effective and to 2) examine the effects of LIFU on dAI BOLD activity and craving in response to cocaine cue-exposure. The study will screen 60 individuals with Cocaine Use Disorder (CUD) to arrive at 30 enrolled subjects, based on a 2:1 screen/randomization ratio.
Primary Outcome
Evidence on MRI of BOLD activity in the dAI region
Interventions
- DEVICE Low-Intensity Focused Ultrasound
- DEVICE Sham LIFU device
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2023-03-24 |
| Est. Completion | 2025-08-31 |
| Phase | NA |
What the finished NCT05857852 record still lists
NCT05857852 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Low-Intensity Focused Ultrasound is the first listed.
NCT05857852 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05857852 about?
NCT05857852 is a clinical study titled "Low-Intensity Focused Ultrasound for Cocaine Use Disorder". This study aims to understand the role of Low-Intensity Focused Ultrasound on craving levels for cocaine as evidenced by diagnostic imaging of the dorsal anterior insula (dAI) and subjective ratings. Data analysis will serve to show if 1) LIFU is safe and effective and to 2) examine the effects of L...
What is the current status of trial NCT05857852?
This trial is currently completed. It is a NA study. The enrollment target is 25 participants. The study started on 2023-03-24. Estimated completion is 2025-08-31.
What interventions are being tested in trial NCT05857852?
The interventions under investigation include: Low-Intensity Focused Ultrasound (DEVICE), Sham LIFU device (DEVICE).
Who is sponsoring clinical trial NCT05857852?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05857852's enrollment target sits among peer trials
25 1712th of 2000 higher than 265 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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