Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05844384 · ClinicalTrials.gov registry record · NA
Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial
A NA study of Ocular Hypertension and Primary Open Angle Glaucoma, sponsored by 59th Medical Wing.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT05844384: Recruiting NA study of Ocular Hypertension and Primary Open Angle Glaucoma, sponsored by 59th Medical Wing.
NCT05844384 is a NA study of Ocular Hypertension and Primary Open Angle Glaucoma that is actively recruiting participants, run by 59th Medical Wing. The registered enrollment target is 30 participants, below the 278-participant average among 54 other Ocular Hypertension trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05844384, a NA study of Ocular Hypertension and Primary Open Angle Glaucoma, is actively recruiting participants, sponsored by 59th Medical Wing.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This randomized, single-masked, crossover, non-inferiority trial aims to evaluate the safety and efficacy of Nanodropper-mediated microdrops of ocular hypotensive topical treatments (experimental intervention) compared to standard drops of the same medication(s) (active comparator) in Wilford Hall Ambulatory Surgical Center (WHASC) primary open-angle glaucoma (POAG) and ocular hypertension (OHTN) patients.
Primary Outcome
Change in mean intraocular pressure (unit = mmHg) from baseline to month 6 measure with applanation tonometer
Conditions Studied
Interventions
- DEVICE Nanodropper
- DEVICE Regular dropper
Study Locations (1)
Texas
- Wilford Hall Ambulatory Surgical Center - Lackland Air Force Base
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2022-03-17 |
| Est. Completion | 2024-03-17 |
| Phase | NA |
What NCT05844384 shows while recruiting
NCT05844384 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 278-participant average among 54 other Ocular Hypertension trials with a reported enrollment target (89% lower).
The record links to 2 conditions, with Ocular Hypertension appearing as the primary indexed condition, and to 2 interventions - of which Nanodropper is the first listed.
NCT05844384 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05844384 about?
NCT05844384 is a clinical study titled "Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial". This randomized, single-masked, crossover, non-inferiority trial aims to evaluate the safety and efficacy of Nanodropper-mediated microdrops of ocular hypotensive topical treatments (experimental intervention) compared to standard drops of the same medication(s) (active comparator) in Wilford Hall A...
What is the current status of trial NCT05844384?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2022-03-17. Estimated completion is 2024-03-17.
What conditions does trial NCT05844384 study?
This clinical trial studies the following conditions: Ocular Hypertension, Primary Open Angle Glaucoma.
What interventions are being tested in trial NCT05844384?
The interventions under investigation include: Nanodropper (DEVICE), Regular dropper (DEVICE).
Who is sponsoring clinical trial NCT05844384?
This trial is sponsored by 59th Medical Wing, which has 20 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05844384 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Ocular Hypertension
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05844384's enrollment target sits among peer trials
30 49th of 54 higher than 5 of 54 other Ocular Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ocular Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Implementing AI-based Glaucoma Screening Within Federally Qualified Health Centers
RECRUITING · NA
-
The Effect of a Scleral Lens on the Anterior Chamber Depth and Minimum Rim Width
COMPLETED · NA
-
Effects of a Single OMT on Intraocular Pressure (IOP) in Ocular Hypertenive or Glaucoma Suspect Subjects
COMPLETED · NA
-
DSLT for Reducing Medication in Glaucoma
RECRUITING
-
24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients
RECRUITING · Phase 4
-
24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring
RECRUITING
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00977977 · 30 participants · Phase 2
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
- NCT01459107 · 30 participants · Phase 2
Human Upper Extremity Allotransplantation
- NCT01666080 · 30 participants · NA
Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)
- NCT01720836 · 30 participants · Phase 1
Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI