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NCT05826418 · ClinicalTrials.gov registry record · NA
Dietary Optimization of Microbiome Recovery Following Fecal Microbiota Transplantation
A NA study, sponsored by University of Minnesota.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
NCT05826418: Completed NA study, sponsored by University of Minnesota.
NCT05826418 is a NA study that has completed, run by University of Minnesota. The registered enrollment target is 12 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05826418, a NA study, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
Study Summary
Recurrent Clostridioides difficle infection (rCDI) is a very significant problem in its own right and current fecal microbiota transplant (FMT) -based therapeutics will benefit from their optimization for this indication. It is likely that appropriate nutritional support coupled with microbiota-based drugs will yield superior clinical outcomes. However, both diet and gut microbiome are very complex. This project, which is based on a wealth of FMT experience, both clinical and investigational, over the past decade along with the novel techniques developed to identify dietary patterns and food groups that explain the most variation in gut microbiome, offers an ideal platform for performing systematic research in nutritional support that promotes gut microbiota health. The purpose is to Generate preliminary data with regards to tolerability of the Microbiota enhancing and nourishing diet (MEND) and its effects on the fecal microbiota in rCDI patients following FMT with the goal of developing larger clinical trials aimed to optimize post-FMT dietary management.
Primary Outcome
Diet acceptability questionnaire: Includes 7 questions each with minimum and maximum values (1 and 7) and higher scores mean better outcomes.
Interventions
- DIETARY_SUPPLEMENT MEND diet
- DIETARY_SUPPLEMENT mNICE diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2023-05-01 |
| Est. Completion | 2024-03-12 |
| Phase | NA |
What the finished NCT05826418 record still lists
NCT05826418 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which MEND diet is the first listed.
NCT05826418 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05826418 about?
NCT05826418 is a clinical study titled "Dietary Optimization of Microbiome Recovery Following Fecal Microbiota Transplantation". Recurrent Clostridioides difficle infection (rCDI) is a very significant problem in its own right and current fecal microbiota transplant (FMT) -based therapeutics will benefit from their optimization for this indication. It is likely that appropriate nutritional support coupled with microbiota-base...
What is the current status of trial NCT05826418?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2023-05-01. Estimated completion is 2024-03-12.
What interventions are being tested in trial NCT05826418?
The interventions under investigation include: MEND diet (DIETARY_SUPPLEMENT), mNICE diet (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT05826418?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05826418's enrollment target sits among peer trials
12 1913th of 2000 higher than 74 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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