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NCT05817435 · ClinicalTrials.gov registry record · Phase 1

A Phase 1 Bioequivalence Study of Efgartigimod PH20 SC Administered Via a Prefilled Syringe Versus a Vial+Syringe Presentation in Healthy Adults

A Phase 1 study of Bioequivalence, sponsored by argenx.

Completed
Registry status
Phase 1
Development phase
120
Enrollment target
2
Study locations

NCT05817435 is a Phase 1 study of Bioequivalence that has completed, run by argenx. The registered enrollment target is 120 participants, above the 32-participant average among 3 other Bioequivalence trials with a reported enrollment target (275% higher). The trial reports 2 study locations across 2 states.

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The verdict

NCT05817435, a Phase 1 study of Bioequivalence, has completed, sponsored by argenx.

COMPLETED
Registry status
Phase 1
Development phase
120 participants
Enrollment target
2
Study locations

Study Summary

This is a randomized, open-label, parallel-group, single-dose study comparing the pharmacokinetics of efgartigimod in blood following a single administration of efgartigimod PH20 SC via a prefilled syringe versus a vial + syringe in healthy participants.

Conditions Studied

Interventions

  • BIOLOGICAL efgartigimod PH20 SC as a prefilled syringe presentation
  • BIOLOGICAL efgartigimod PH20 SC as a vial + syringe presentation

Study Locations (2)

Arizona

  • Investigator site 0010209 - Tempe

Nebraska

  • Investigator site 0010208 - Lincoln

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2023-03-13
Est. Completion 2023-05-12
Phase Phase 1

Sponsor

argenx

49 total trials

What the Registry Record Tells You About NCT05817435

The ClinicalTrials.gov registry entry for NCT05817435 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 32-participant average among 3 other Bioequivalence trials with a reported enrollment target (275% higher). The listed sponsor is argenx, which has 49 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Bioequivalence appearing as the primary indexed condition, and to 2 interventions - of which efgartigimod PH20 SC as a prefilled syringe presentation is the first listed.

NCT05817435 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Arizona, Nebraska.

Frequently Asked Questions

What is clinical trial NCT05817435 about?

NCT05817435 is a clinical study titled "A Phase 1 Bioequivalence Study of Efgartigimod PH20 SC Administered Via a Prefilled Syringe Versus a Vial+Syringe Presentation in Healthy Adults". This is a randomized, open-label, parallel-group, single-dose study comparing the pharmacokinetics of efgartigimod in blood following a single administration of efgartigimod PH20 SC via a prefilled syringe versus a vial + syringe in healthy participants.

What is the current status of trial NCT05817435?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 120 participants. The study started on 2023-03-13. Estimated completion is 2023-05-12.

What conditions does trial NCT05817435 study?

This clinical trial studies the following conditions: Bioequivalence.

What interventions are being tested in trial NCT05817435?

The interventions under investigation include: efgartigimod PH20 SC as a prefilled syringe presentation (BIOLOGICAL), efgartigimod PH20 SC as a vial + syringe presentation (BIOLOGICAL).

Who is sponsoring clinical trial NCT05817435?

This trial is sponsored by argenx, which has 49 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05817435 being conducted?

This trial has 2 study locations across Arizona, Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.