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NCT05809323 · ClinicalTrials.gov registry record · NA

Marfan Syndrome Moderate Exercise Trial II

A NA study of Marfan Syndrome, sponsored by Baylor College of Medicine.

Recruiting
Registry status
NA
Development phase
50
Enrollment target
1
Study location

NCT05809323 is a NA study of Marfan Syndrome that is actively recruiting participants, run by Baylor College of Medicine. The registered enrollment target is 50 participants, below the 390-participant average among 4 other Marfan Syndrome trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05809323, a NA study of Marfan Syndrome, is actively recruiting participants, sponsored by Baylor College of Medicine.

RECRUITING
Registry status
NA
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

Marfan syndrome (MFS) is a distinctive connective tissue disorder that affects multiple organ systems including the heart, bones, ligaments, and eyes, and is associated with significant risk of aortic dissection. Given limited evidence from in-vitro studies, and theoretical concerns, the majority of patients with MFS are restricted from certain physical activities. The lack of exercise and deconditioning have detrimental effects including increasing weakness, joint pain, decreased endurance, and depressive symptoms. Given the significant paucity of data currently existing on the effects of exercise in humans with MFS, and the recent, optimistic findings in rodent models, this pilot trial was established to assess the effects of moderated dynamic exercise in adolescents and young adults with MFS.

Conditions Studied

Interventions

  • OTHER Control Group
  • OTHER Exercise Intervention Group

Study Locations (1)

Texas

  • Texas Children's Hospital - Houston

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2023-09-01
Est. Completion 2027-07-01
Phase NA

Sponsor

Baylor College of Medicine

616 total trials

What the Registry Record Tells You About NCT05809323

The ClinicalTrials.gov registry entry for NCT05809323 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 390-participant average among 4 other Marfan Syndrome trials with a reported enrollment target (87% lower). The listed sponsor is Baylor College of Medicine, which has 616 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Marfan Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Control Group is the first listed.

NCT05809323 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT05809323 about?

NCT05809323 is a clinical study titled "Marfan Syndrome Moderate Exercise Trial II". Marfan syndrome (MFS) is a distinctive connective tissue disorder that affects multiple organ systems including the heart, bones, ligaments, and eyes, and is associated with significant risk of aortic dissection. Given limited evidence from in-vitro studies, and theoretical concerns, the majority of...

What is the current status of trial NCT05809323?

This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2023-09-01. Estimated completion is 2027-07-01.

What conditions does trial NCT05809323 study?

This clinical trial studies the following conditions: Marfan Syndrome.

What interventions are being tested in trial NCT05809323?

The interventions under investigation include: Control Group (OTHER), Exercise Intervention Group (OTHER).

Who is sponsoring clinical trial NCT05809323?

This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05809323 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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