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NCT05798481 · ClinicalTrials.gov registry record · Early Phase 1
Effect of Sublingually Generated S-nitroso-N-acetylcysteine on Systemic Blood Pressure.
A Early Phase 1 study, sponsored by University of Alabama at Birmingham.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 14
- Enrollment target
NCT05798481 is a Early Phase 1 study that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 14 participants.
The verdict
NCT05798481, a Early Phase 1 study, has completed, sponsored by University of Alabama at Birmingham.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 14 participants
- Enrollment target
Study Summary
The purpose of the study is to increase the in vivo levels of nitric oxide by generating nitric oxide donor compound S-nitrosoacetylcysteine (SNOAC) using the mixture of sodium nitrite and N-acetylcysteine crystals in the sublingual space. The generated SNOAC rapidly diffuses into blood circulation thereby decrease the systemic blood pressure. This compound can be an alternative to organic nitrate NO donor drugs without developing tolerance in patients.
Interventions
- DRUG Mixture of Sodium Nitrite and N-acetylcysteine (NAC) crytals.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2024-03-27 |
| Est. Completion | 2025-10-05 |
| Phase | Early Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05798481
The ClinicalTrials.gov registry entry for NCT05798481 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Alabama at Birmingham, which has 1,160 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Mixture of Sodium Nitrite and N-acetylcysteine (NAC) crytals. is the first listed.
NCT05798481 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05798481 about?
NCT05798481 is a clinical study titled "Effect of Sublingually Generated S-nitroso-N-acetylcysteine on Systemic Blood Pressure.". The purpose of the study is to increase the in vivo levels of nitric oxide by generating nitric oxide donor compound S-nitrosoacetylcysteine (SNOAC) using the mixture of sodium nitrite and N-acetylcysteine crystals in the sublingual space. The generated SNOAC rapidly diffuses into blood circulation ...
What is the current status of trial NCT05798481?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 14 participants. The study started on 2024-03-27. Estimated completion is 2025-10-05.
What interventions are being tested in trial NCT05798481?
The interventions under investigation include: Mixture of Sodium Nitrite and N-acetylcysteine (NAC) crytals. (DRUG).
Who is sponsoring clinical trial NCT05798481?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
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