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NCT05796557 · ClinicalTrials.gov registry record · Phase 4
ECMO Hemostatic Transfusions in Children
A Phase 4 study, sponsored by Yale University.
- Completed
- Registry status
- Phase 4
- Development phase
- 50
- Enrollment target
NCT05796557: Completed Phase 4 study, sponsored by Yale University.
NCT05796557 is a Phase 4 study that has completed, run by Yale University. The registered enrollment target is 50 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05796557, a Phase 4 study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 50 participants
- Enrollment target
Study Summary
Critically ill children supported by extracorporeal membrane oxygenation (ECMO) receive large volumes of prophylactic platelet transfusions to prevent bleeding. However, mounting evidence has demonstrated significant morbidity and mortality associated with these transfusions. The ECmo hemoSTAtic Transfusions In Children (ECSTATIC) pilot trial will test two different platelet transfusion strategies, based on two different platelet counts thresholds, one high (higher platelet transfusion strategy) and one low (lower platelet transfusion strategy). The pilot will gather the necessary information to perform a full trial which will provide a better understanding of how to transfuse platelets to children supported by ECMO and reduce the associated morbidity.
Primary Outcome
The total dose (in mL/kg/day) will be computed by the research team, by dividing the total platelet transfusion volume by the patient's weight at admission and the number of days of intervention.
Interventions
- BIOLOGICAL Platelet Transfusion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2023-12-12 |
| Est. Completion | 2025-03-25 |
| Phase | Phase 4 |
What the finished NCT05796557 record still lists
NCT05796557 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 1 intervention - of which Platelet Transfusion is the first listed.
NCT05796557 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05796557 about?
NCT05796557 is a clinical study titled "ECMO Hemostatic Transfusions in Children". Critically ill children supported by extracorporeal membrane oxygenation (ECMO) receive large volumes of prophylactic platelet transfusions to prevent bleeding. However, mounting evidence has demonstrated significant morbidity and mortality associated with these transfusions. The ECmo hemoSTAtic Tra...
What is the current status of trial NCT05796557?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 50 participants. The study started on 2023-12-12. Estimated completion is 2025-03-25.
What interventions are being tested in trial NCT05796557?
The interventions under investigation include: Platelet Transfusion (BIOLOGICAL).
Who is sponsoring clinical trial NCT05796557?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05796557's enrollment target sits among peer trials
50 1255th of 2000 higher than 678 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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