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NCT05773040 · ClinicalTrials.gov registry record · Phase 1

A Phase 1 Study of JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas

A Phase 1 study of Lymphomas and B-cell Lymphomas, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 1
Development phase
33
Enrollment target
1
Study location

NCT05773040 is a Phase 1 study of Lymphomas and B-cell Lymphomas that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 33 participants, below the 1,090-participant average among 7 other Lymphomas trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05773040, a Phase 1 study of Lymphomas and B-cell Lymphomas, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 1
Development phase
33 participants
Enrollment target
1
Study location

Study Summary

To find the highest tolerable dose of JV-213 (a type of autologous CAR T cell therapy) that can be given to patients who have B-cell lymphoma that is relapsed or refractory.

Conditions Studied

Lymphomas B-cell Lymphomas

Interventions

  • PROCEDURE Leukapheresis
  • DRUG JV-213

Study Locations (1)

Texas

  • The University of Texas M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 33 participants
Start Date 2023-04-14
Est. Completion 2027-12-31
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05773040

The ClinicalTrials.gov registry entry for NCT05773040 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 33 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,090-participant average among 7 other Lymphomas trials with a reported enrollment target (97% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Lymphomas appearing as the primary indexed condition, and to 2 interventions - of which Leukapheresis is the first listed.

NCT05773040 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT05773040 about?

NCT05773040 is a clinical study titled "A Phase 1 Study of JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas". To find the highest tolerable dose of JV-213 (a type of autologous CAR T cell therapy) that can be given to patients who have B-cell lymphoma that is relapsed or refractory.

What is the current status of trial NCT05773040?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 33 participants. The study started on 2023-04-14. Estimated completion is 2027-12-31.

What conditions does trial NCT05773040 study?

This clinical trial studies the following conditions: Lymphomas, B-cell Lymphomas.

What interventions are being tested in trial NCT05773040?

The interventions under investigation include: Leukapheresis (PROCEDURE), JV-213 (DRUG).

Who is sponsoring clinical trial NCT05773040?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05773040 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.