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Assess the Oral Bioavailability of New ABT-263 Formulations
NCT00743028 · View on ClinicalTrials.gov ↗
Study Summary
This is a randomized, open-label, multicenter crossover study to determine the oral bioavailability of new ABT-263 formulations relative to that of the current ABT-263 formulation being administered in ongoing Phase 1/2a studies. Approximately 36 evaluable subjects with lymphoid malignancies, including chronic lymphocytic leukemia, and solid tumors will be enrolled in this study.
Conditions Studied
Interventions
- DRUG ABT-263
Study Locations (5)
California
- Site Reference ID/Investigator# 10281 — Encinitas
- Site Reference ID/Investigator# 10282 — Santa Monica
Maryland
- Site Reference ID/Investigator# 16341 — Bethesda
New Hampshire
- Site Reference ID/Investigator# 9441 — Lebanon
New Jersey
- Site Reference ID/Investigator# 20041 — Hackensack
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2008-08 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00743028
The ClinicalTrials.gov registry entry for NCT00743028 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Abbott, which has 43 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Chronic Lymphocytic Leukemia appearing as the primary indexed condition, and to 1 intervention — of which ABT-263 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00743028 reports 5 study locations spanning 4 distinct geographic areas — top geographies include California, Maryland, New Hampshire. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00743028 about?
NCT00743028 is a clinical study titled "Assess the Oral Bioavailability of New ABT-263 Formulations". This is a randomized, open-label, multicenter crossover study to determine the oral bioavailability of new ABT-263 formulations relative to that of the current ABT-263 formulation being administered in ongoing Phase 1/2a studies. Approximately 36 evaluable subjects with lymphoid malignancies, includ...
What is the current status of trial NCT00743028?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2008-08.
What conditions does trial NCT00743028 study?
This clinical trial studies the following conditions: Chronic Lymphocytic Leukemia, Lymphomas, Leukemias. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00743028?
The interventions under investigation include: ABT-263 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00743028?
This trial is sponsored by Abbott, which has 43 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00743028 being conducted?
This trial has 5 study locations across California, Maryland, New Hampshire, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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