Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00743028 · ClinicalTrials.gov registry record · Phase 1

Assess the Oral Bioavailability of New ABT-263 Formulations

A Phase 1 study of Chronic Lymphocytic Leukemia and Lymphomas, sponsored by Abbott.

Completed
Registry status
Phase 1
Development phase
36
Enrollment target
5
Study locations

NCT00743028: Completed Phase 1 study of Chronic Lymphocytic Leukemia and Lymphomas, sponsored by Abbott.

NCT00743028 is a Phase 1 study of Chronic Lymphocytic Leukemia and Lymphomas that has completed, run by Abbott. The registered enrollment target is 36 participants, below the 182-participant average among 187 other Chronic Lymphocytic Leukemia trials with a reported enrollment target (80% lower). The trial reports 5 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00743028, a Phase 1 study of Chronic Lymphocytic Leukemia and Lymphomas, has completed, sponsored by Abbott.

COMPLETED
Registry status
Phase 1
Development phase
36 participants
Enrollment target
5
Study locations

Study Summary

This is a randomized, open-label, multicenter crossover study to determine the oral bioavailability of new ABT-263 formulations relative to that of the current ABT-263 formulation being administered in ongoing Phase 1/2a studies. Approximately 36 evaluable subjects with lymphoid malignancies, including chronic lymphocytic leukemia, and solid tumors will be enrolled in this study.

Interventions

  • DRUG ABT-263

Study Locations (5)

California

  • Site Reference ID/Investigator# 10281 - Encinitas
  • Site Reference ID/Investigator# 10282 - Santa Monica

Maryland

  • Site Reference ID/Investigator# 16341 - Bethesda

New Hampshire

  • Site Reference ID/Investigator# 9441 - Lebanon

New Jersey

  • Site Reference ID/Investigator# 20041 - Hackensack

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2008-08
Phase Phase 1
Abbott

181 total trials

What the finished NCT00743028 record still lists

NCT00743028 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 182-participant average among 187 other Chronic Lymphocytic Leukemia trials with a reported enrollment target (80% lower).

The record links to 3 conditions, with Chronic Lymphocytic Leukemia appearing as the primary indexed condition, and to 1 intervention - of which ABT-263 is the first listed.

NCT00743028 lists 5 locations in 4 states (California, Maryland, New Hampshire).

Frequently Asked Questions

What is clinical trial NCT00743028 about?

NCT00743028 is a clinical study titled "Assess the Oral Bioavailability of New ABT-263 Formulations". This is a randomized, open-label, multicenter crossover study to determine the oral bioavailability of new ABT-263 formulations relative to that of the current ABT-263 formulation being administered in ongoing Phase 1/2a studies. Approximately 36 evaluable subjects with lymphoid malignancies, includ...

What is the current status of trial NCT00743028?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2008-08.

What conditions does trial NCT00743028 study?

This clinical trial studies the following conditions: Chronic Lymphocytic Leukemia, Lymphomas, Leukemias.

What interventions are being tested in trial NCT00743028?

The interventions under investigation include: ABT-263 (DRUG).

Who is sponsoring clinical trial NCT00743028?

This trial is sponsored by Abbott, which has 181 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00743028 being conducted?

This trial has 5 study locations across California, Maryland, New Hampshire, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Chronic Lymphocytic Leukemia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00743028's enrollment target sits among peer trials

36 123rd of 187 higher than 64 of 187 other Chronic Lymphocytic Leukemia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Chronic Lymphocytic Leukemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00929006 · 36 participants · Early Phase 1

    Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism

  • NCT01891318 · 36 participants · Phase 1

    Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

  • NCT02291848 · 36 participants · Phase 1

    Tumor-Associated Antigen-Specific Cytotoxic T-Lymphocytes for Multiple Myeloma

  • NCT02366819 · 36 participants · Phase 4

    Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00743028, the US trial registry maintained by the National Library of Medicine. NCT00743028 (small enrollment · multi site footprint · completed) retrieved and formatted by PlainTrial, see methodology.