Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05773014 · ClinicalTrials.gov registry record · NA
Digital vs. Speculum Exams for PPROM
A NA study of PPROM, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- NA
- Development phase
- 86
- Enrollment target
- 1
- Study location
NCT05773014: Recruiting NA study of PPROM, sponsored by Washington University School of Medicine.
NCT05773014 is a NA study of PPROM that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 86 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05773014, a NA study of PPROM, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- NA
- Development phase
- 86 participants
- Enrollment target
- 1
- Study location
Study Summary
After preterm prelabor rupture of membranes (PPROM)\[breaking of the amniotic sac prior to 37 weeks gestation in pregnancy\], patients are recommended for inpatient admission and close monitoring for complications including preterm labor, intraamniotic infection (infection of the sac around the baby), and placental abruption (separation of the placenta from wall of the uterus). When evaluation of cervical dilation is clinically indicated, obstetricians traditionally perform sterile speculum exams due to concern for decrease in pregnancy latency (length of time between breaking the water and delivery) with sterile digital exams in retrospective studies. These studies are concerning, however, by the indications for the exams and are at risk for confounding by indication. This is a randomized, non-inferiority trial to examine if sterile digital versus speculum exams effect latency of pregnancy in patients with PPROM.
Primary Outcome
time from admission to delivery
Conditions Studied
Interventions
- PROCEDURE Speculum Exams
- PROCEDURE Digital Exams
Study Locations (1)
Missouri
- Barnes Jewish Hospital - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 86 participants |
| Start Date | 2023-03-27 |
| Est. Completion | 2027-07-01 |
| Phase | NA |
What NCT05773014 shows while recruiting
NCT05773014 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 86 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 1 condition, with PPROM appearing as the primary indexed condition, and to 2 interventions - of which Speculum Exams is the first listed.
NCT05773014 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT05773014 about?
NCT05773014 is a clinical study titled "Digital vs. Speculum Exams for PPROM". After preterm prelabor rupture of membranes (PPROM)\[breaking of the amniotic sac prior to 37 weeks gestation in pregnancy\], patients are recommended for inpatient admission and close monitoring for complications including preterm labor, intraamniotic infection (infection of the sac around the baby...
What is the current status of trial NCT05773014?
This trial is currently recruiting. It is a NA study. The enrollment target is 86 participants. The study started on 2023-03-27. Estimated completion is 2027-07-01.
What conditions does trial NCT05773014 study?
This clinical trial studies the following conditions: PPROM.
What interventions are being tested in trial NCT05773014?
The interventions under investigation include: Speculum Exams (PROCEDURE), Digital Exams (PROCEDURE).
Who is sponsoring clinical trial NCT05773014?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05773014 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05773014's enrollment target sits among peer trials
86 977th of 2000 higher than 1,021 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01639508 · 86 participants · Phase 2
Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity
- NCT03519269 · 86 participants · NA
Navio Robotic Versus Conventional Total Knee Arthroplasty
- NCT04132999 · 86 participants · NA
PAP for Children With DS and OSAS
- NCT04545957 · 86 participants · NA
Jump: MR Simulation For Radiation Therapy Master Protocol
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI