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NCT05771675 · ClinicalTrials.gov registry record · Early Phase 1
Simvastatin Treatment to Improve Patient-reported Outcomes in Patients With Chronic Pancreatitis
A Early Phase 1 study of Chronic Pancreatitis and Recurrent Acute Pancreatitis, sponsored by Cedars-Sinai Medical Center.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 90
- Enrollment target
- 5
- Study locations
NCT05771675: Recruiting Early Phase 1 study of Chronic Pancreatitis and Recurrent Acute Pancreatitis, sponsored by Cedars-Sinai Medical Center.
NCT05771675 is a Early Phase 1 study of Chronic Pancreatitis and Recurrent Acute Pancreatitis that is actively recruiting participants, run by Cedars-Sinai Medical Center. The registered enrollment target is 90 participants, below the 687-participant average among 42 other Chronic Pancreatitis trials with a reported enrollment target (87% lower). The trial reports 5 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05771675, a Early Phase 1 study of Chronic Pancreatitis and Recurrent Acute Pancreatitis, is actively recruiting participants, sponsored by Cedars-Sinai Medical Center.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 90 participants
- Enrollment target
- 5
- Study locations
Study Summary
The purpose of this pilot study to examine the feasibility and acceptability of simvastatin in adults with Recurrent Acute Pancreatitis (RAP) and Chronic Pancreatitis (CP).
Primary Outcome
A priori thresholds to evaluate feasibility are: 50% enrollment, \<15% attrition, \>75% adherence with doses, \<20% side effects. A score of \>75% acceptability ratings per an "Acceptability Form" that will be provided during the last visit will be used to gauge the general acceptability of the intervention (Simvastatin or Placebo) and study procedures to each participating subject.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Simvastatin
Study Locations (5)
California
- University of Southern California - Los Angeles
- Cedars-Sinai Medical Center - Los Angeles
- Stanford University - Stanford
Ohio
- Ohio State University - Columbus
Pennsylvania
- University of Pittsburgh Medical Center - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2024-10-24 |
| Est. Completion | 2027-06 |
| Phase | Early Phase 1 |
What NCT05771675 shows while recruiting
NCT05771675 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 687-participant average among 42 other Chronic Pancreatitis trials with a reported enrollment target (87% lower).
The record links to 2 conditions, with Chronic Pancreatitis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05771675 lists 5 locations in 3 states (California, Ohio, Pennsylvania).
Frequently Asked Questions
What is clinical trial NCT05771675 about?
NCT05771675 is a clinical study titled "Simvastatin Treatment to Improve Patient-reported Outcomes in Patients With Chronic Pancreatitis". The purpose of this pilot study to examine the feasibility and acceptability of simvastatin in adults with Recurrent Acute Pancreatitis (RAP) and Chronic Pancreatitis (CP).
What is the current status of trial NCT05771675?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 90 participants. The study started on 2024-10-24. Estimated completion is 2027-06.
What conditions does trial NCT05771675 study?
This clinical trial studies the following conditions: Chronic Pancreatitis, Recurrent Acute Pancreatitis.
What interventions are being tested in trial NCT05771675?
The interventions under investigation include: Placebo (DRUG), Simvastatin (DRUG).
Who is sponsoring clinical trial NCT05771675?
This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05771675 being conducted?
This trial has 5 study locations across California, Ohio, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pancreatitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05771675's enrollment target sits among peer trials
90 18th of 42 higher than 24 of 42 other Chronic Pancreatitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pancreatitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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