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NCT05747469 · ClinicalTrials.gov registry record · Early Phase 1
Use of Allograft Adipose Matrix for Small Joint Arthritis of the Hand
A Early Phase 1 study of Osteoarthritis Hand, sponsored by Cedars-Sinai Medical Center.
- Active
- Registry status
- Early Phase 1
- Development phase
- 34
- Enrollment target
- 1
- Study location
NCT05747469: Active Early Phase 1 study of Osteoarthritis Hand, sponsored by Cedars-Sinai Medical Center.
NCT05747469 is a Early Phase 1 study of Osteoarthritis Hand that is active but no longer recruiting, run by Cedars-Sinai Medical Center. The registered enrollment target is 34 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (36% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05747469, a Early Phase 1 study of Osteoarthritis Hand, is active but no longer recruiting, sponsored by Cedars-Sinai Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 34 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose the research is to evaluate the safety and efficacy of injection of adipose allograft matrix (AAM) to the small joints of the hand for treatment of early stage osteoarthritis. The hypothesis is that use of AAM injected directly into the joint will show improvements in pain and disability while providing a safe, off-the-shelf alternative which can obviate the need for, and risks associated with, current treatment options with autologous fat transfer. As standard of care, routine strength, pain scale scores (VAS) and range of motion will be recorded, a baseline disability survey (DASH score) will also be administered. After these have all been recorded and administered in a separate visit the patient will undergo the lipofilling procedure. The subject population will include patients over the age of 18 who present with joint pain of the hand with radiographic evidence of osteoarthritis.
Primary Outcome
Measured with a standardized goniometer
Conditions Studied
Interventions
- DRUG local anaesthetic injection
- PROCEDURE Human Adipose Allograft
Study Locations (1)
California
- Cedars-Sinai Medical Center - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2023-08-28 |
| Est. Completion | 2027-01-01 |
| Phase | Early Phase 1 |
What the registry record for NCT05747469 still lists
NCT05747469 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (36% lower).
The record links to 1 condition, with Osteoarthritis Hand appearing as the primary indexed condition, and to 2 interventions - of which local anaesthetic injection is the first listed.
NCT05747469 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05747469 about?
NCT05747469 is a clinical study titled "Use of Allograft Adipose Matrix for Small Joint Arthritis of the Hand". The purpose the research is to evaluate the safety and efficacy of injection of adipose allograft matrix (AAM) to the small joints of the hand for treatment of early stage osteoarthritis. The hypothesis is that use of AAM injected directly into the joint will show improvements in pain and disability...
What is the current status of trial NCT05747469?
This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 34 participants. The study started on 2023-08-28. Estimated completion is 2027-01-01.
What conditions does trial NCT05747469 study?
This clinical trial studies the following conditions: Osteoarthritis Hand.
What interventions are being tested in trial NCT05747469?
The interventions under investigation include: local anaesthetic injection (DRUG), Human Adipose Allograft (PROCEDURE).
Who is sponsoring clinical trial NCT05747469?
This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05747469 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis Hand
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05747469's enrollment target sits among peer trials
34 748th of 2000 higher than 1,239 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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