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NCT05736471 · ClinicalTrials.gov registry record

Cognitive and Affective Processes Online

A clinical trial of Depression, sponsored by University of Minnesota.

Recruiting
Registry status
2,500
Enrollment target
1
Study location

NCT05736471: Recruiting study of Depression, sponsored by University of Minnesota.

NCT05736471 is a study of Depression that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 2,500 participants, above the 783-participant average among 679 other Depression trials with a reported enrollment target (219% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05736471, a study of Depression, is actively recruiting participants, sponsored by University of Minnesota.

RECRUITING
Registry status
2,500 participants
Enrollment target
1
Study location

Study Summary

This study will provide data for evaluating the psychometric characteristics of the tests assessing cognitive flexibility, including their (1) internal consistency, (2) feasibility and tolerability, their (3) convergent and discriminant validity of cognitive and affective constructs such as those introduced to understand mental disorders, and (4) sensitivity (and correspondence) to individual differences. For these tests to be useful in studying clinical conditions, they must show adequate reliability, validity, and sensitivity in large samples of convenience.

Primary Outcome

Relationship of model-based measures of learning from the past and anticipating the future to symptoms of depression, specifically anhedonia

Conditions Studied

Interventions

  • DIAGNOSTIC_TEST Computational dissociation of the causes of cognitive rigidity in depression

Study Locations (1)

Minnesota

  • University of Minnesota - Minneapolis

Trial Details

FieldValue
Enrollment Target 2,500 participants
Start Date 2023-02-15
Est. Completion 2026-05-02
University of Minnesota

966 total trials

What NCT05736471 shows while recruiting

NCT05736471 is an observational study that tracks outcomes without assigning an intervention. Its 2,500 participants enrollment target places it among the larger protocols in the corpus, above the 783-participant average among 679 other Depression trials with a reported enrollment target (219% higher).

The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Computational dissociation of the causes of cognitive rigidity in depression is the first listed.

NCT05736471 reports a single indexed study location in Minnesota.

Frequently Asked Questions

What is clinical trial NCT05736471 about?

NCT05736471 is a clinical study titled "Cognitive and Affective Processes Online". This study will provide data for evaluating the psychometric characteristics of the tests assessing cognitive flexibility, including their (1) internal consistency, (2) feasibility and tolerability, their (3) convergent and discriminant validity of cognitive and affective constructs such as those in...

What is the current status of trial NCT05736471?

This trial is currently recruiting. The enrollment target is 2,500 participants. The study started on 2023-02-15. Estimated completion is 2026-05-02.

What conditions does trial NCT05736471 study?

This clinical trial studies the following conditions: Depression.

What interventions are being tested in trial NCT05736471?

The interventions under investigation include: Computational dissociation of the causes of cognitive rigidity in depression (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT05736471?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05736471 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Depression

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05736471's enrollment target sits among peer trials

2,500 22nd of 679 higher than 657 of 679 other Depression trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05736471, the US trial registry maintained by the National Library of Medicine. NCT05736471 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.