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NCT05727332 · ClinicalTrials.gov registry record · NA
Vascular Adaptations to Single-Sprint Training
A NA study of Cardiovascular System, sponsored by University of Mississippi, Oxford.
- Completed
- Registry status
- NA
- Development phase
- 46
- Enrollment target
- 1
- Study location
NCT05727332 is a NA study of Cardiovascular System that has completed, run by University of Mississippi, Oxford. The registered enrollment target is 46 participants. The trial reports 1 study location across 1 state.
The verdict
NCT05727332, a NA study of Cardiovascular System, has completed, sponsored by University of Mississippi, Oxford.
- COMPLETED
- Registry status
- NA
- Development phase
- 46 participants
- Enrollment target
- 1
- Study location
Study Summary
The long-term objective of this research line is to identify and implement an effective and feasible intervention capable of preventing and/or reducing the burden of cardiometabolic and obesity-related diseases that affect Mississippians and others. The pursuit of this long-term objective will begin with achieving the specific aims proposed in this pilot project, which are to determine the effect of single sprint training for improving (1) systemic macro-vascular function, (2) local and systemic micro-vascular function, and (3) cardiorespiratory fitness. These aims will be achieved using a randomized controlled trial whereby 40 males and females will be randomized into an intervention group (n=20) or time-matched negative control group (n=20). The intervention group will perform a single maximal effort sprint on a cycle ergometer for twenty seconds 3 days/week for 4 weeks and the control group will be asked to maintain pre-intervention habits/behavior over 4 weeks. All outcome measures are non-invasive, and will be assessed pre-, mid-, and post-intervention, with the exception of cardiorespiratory fitness, which will be measured pre- and post-. To achieve aim 1, brachial artery flow-mediated dilation via ultrasonography and systolic and diastolic blood pressure via automated oscillometry will be measured on the arm. To achieve aim 2, post-occlusive reactive hyperemia via near-infrared spectroscopy and reactive hyperemia via ultrasound will be measured in the arm and leg, respectively. To achieve aim 3, pulmonary gas exchange will be measured during a graded exercise test on a cycle ergometer. All outcomes will be compared across time between conditions and sex with a three-way Bayesian Repeated Measures ANOVA using pre-values as covariates and an uninformed prior. 95% credible intervals will also be calculated to power future investigations using this intervention. If the intervention is found effective, future studies will be conducted to determine the efficacy of
Conditions Studied
Interventions
- BEHAVIORAL Single-Sprint Training
Study Locations (1)
Mississippi
- University of Mississippi - University
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2023-06-05 |
| Est. Completion | 2024-12-05 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05727332
The ClinicalTrials.gov registry entry for NCT05727332 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 46 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Mississippi, Oxford, which has 10 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Cardiovascular System appearing as the primary indexed condition, and to 1 intervention - of which Single-Sprint Training is the first listed.
NCT05727332 reports 1 study location spanning 1 distinct geographic area - top geographies include Mississippi.
Frequently Asked Questions
What is clinical trial NCT05727332 about?
NCT05727332 is a clinical study titled "Vascular Adaptations to Single-Sprint Training". The long-term objective of this research line is to identify and implement an effective and feasible intervention capable of preventing and/or reducing the burden of cardiometabolic and obesity-related diseases that affect Mississippians and others. The pursuit of this long-term objective will begin...
What is the current status of trial NCT05727332?
This trial is currently completed. It is a NA study. The enrollment target is 46 participants. The study started on 2023-06-05. Estimated completion is 2024-12-05.
What conditions does trial NCT05727332 study?
This clinical trial studies the following conditions: Cardiovascular System.
What interventions are being tested in trial NCT05727332?
The interventions under investigation include: Single-Sprint Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT05727332?
This trial is sponsored by University of Mississippi, Oxford, which has 10 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05727332 being conducted?
This trial has 1 study location across Mississippi. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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