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NCT05701800 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1468 in Healthy Adults ≥50 Years of Age
A Phase 1 study of Herpes Zoster, sponsored by ModernaTX.
- Active
- Registry status
- Phase 1
- Development phase
- 659
- Enrollment target
- 20
- Study locations
NCT05701800: Active Phase 1 study of Herpes Zoster, sponsored by ModernaTX.
NCT05701800 is a Phase 1 study of Herpes Zoster that is active but no longer recruiting, run by ModernaTX. The registered enrollment target is 659 participants, below the 2,132-participant average among 16 other Herpes Zoster trials with a reported enrollment target (69% lower). The trial reports 20 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05701800, a Phase 1 study of Herpes Zoster, is active but no longer recruiting, sponsored by ModernaTX.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 659 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this first-in-human study is to evaluate the safety and immunogenicity of mRNA-1468.
Conditions Studied
Interventions
- BIOLOGICAL Placebo
- BIOLOGICAL Shingrix
- BIOLOGICAL mRNA-1468
Study Locations (20)
Florida
- Meridien Research - Lakeland
- Clinical Trials of Florida, LLC - Miami
- Floridian Clinical Research - Miami Lakes
- Florida Pulmonary Research Institute, LLC - Winter Park
Texas
- Tekton Research - Austin
- Gadolin Research - Beaumont
- LinQ Research, LLC - Houston
- DM Clinical Research - Tomball
Illinois
- Great Lakes - Chicago
- DM Clinical Research- River Forest - River Forest
California
- Velocity Clinical Research - Westlake - Los Angeles
Colorado
- Tekton Research, Inc - Longmont Center - Longmont
Georgia
- Centricity Research - Columbus
Iowa
- Meridian Clinical Research - Dakota Dunes - Sioux City
Kansas
- Johnson County Clin-Trials (JCCT) - Lenexa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 659 participants |
| Start Date | 2023-01-23 |
| Est. Completion | 2026-06-30 |
| Phase | Phase 1 |
What the registry record for NCT05701800 still lists
NCT05701800 is an interventional study that assigns participants to a tested intervention. The registered 659 participants enrollment target is mid-sized for trials with a published cap, below the 2,132-participant average among 16 other Herpes Zoster trials with a reported enrollment target (69% lower).
The record links to 1 condition, with Herpes Zoster appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT05701800 names 20 study sites across 13 states, led by Florida, Texas, Illinois.
Frequently Asked Questions
What is clinical trial NCT05701800 about?
NCT05701800 is a clinical study titled "A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1468 in Healthy Adults ≥50 Years of Age". The purpose of this first-in-human study is to evaluate the safety and immunogenicity of mRNA-1468.
What is the current status of trial NCT05701800?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 659 participants. The study started on 2023-01-23. Estimated completion is 2026-06-30.
What conditions does trial NCT05701800 study?
This clinical trial studies the following conditions: Herpes Zoster.
What interventions are being tested in trial NCT05701800?
The interventions under investigation include: Placebo (BIOLOGICAL), Shingrix (BIOLOGICAL), mRNA-1468 (BIOLOGICAL).
Who is sponsoring clinical trial NCT05701800?
This trial is sponsored by ModernaTX, which has 90 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05701800 being conducted?
This trial has 20 study locations across California, Colorado, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Herpes Zoster
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05701800's enrollment target sits among peer trials
659 8th of 16 higher than 9 of 16 other Herpes Zoster trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Herpes Zoster trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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