Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05701657 · ClinicalTrials.gov registry record · NA
Nutrition for Precision Health, Powered by the All of Us
A NA study of Nutrition and Dietary Habits, sponsored by RTI International.
- Recruiting
- Registry status
- NA
- Development phase
- 8,000
- Enrollment target
- 14
- Study locations
NCT05701657 is a NA study of Nutrition and Dietary Habits that is actively recruiting participants, run by RTI International. The registered enrollment target is 8,000 participants, above the 2,845-participant average among 22 other Nutrition trials with a reported enrollment target (181% higher). The trial reports 14 study locations across 6 states.
The verdict
NCT05701657, a NA study of Nutrition and Dietary Habits, is actively recruiting participants, sponsored by RTI International.
- RECRUITING
- Registry status
- NA
- Development phase
- 8,000 participants
- Enrollment target
- 14
- Study locations
Study Summary
The goal of this Nutrition for Precision Health (NPH) powered by All of Us research study is to develop Artificial Intelligence/Machine Learning (AI/ML) algorithms that predict individual responses to diet patterns using rich multimodal data streams collected across multiple domains (e.g., behavior, social, environmental, clinical and molecular biomarkers). NPH includes a large phenotyping cohort (Module 1, N=8000) and two separate follow-up groups drawn from a subset of Module 1participants. One group (Module 2, N=1200) receives three distinct diets in a 14-day crossover sequence, with at least a 14-day washout period between diets, while living in their own homes. A second group (Module 3, N=150) receives the same three diets under full-time supervision in a residential research setting. We will train and test AI/ML models to predict 0-4 hour postprandial response curves for glucose, insulin, triglycerides, and GLP-1, to the standardized diet-specific meal test (DSMT) collected after each of the three different diets delivered in Module 2. Each diet functions as a controlled stimulus to reveal biological features (such as individual variables, patterns, or clusters of measurements) that best predict a person's response. The Module 2 DSMT response curves are the primary outcomes (dependent variables) for AI/ML algorithms that predict individual responses to diet patterns. As a secondary objective, NPH will evaluate the validity and acceptability of technology-based dietary assessment tools. The Automated Self-Administered 24-hour recall (ASA24), Automatic Ingestion Monitor-2 (AIM-2), and the mobile food record (mFR) will be evaluated in Modules 2 and 3, and the ASA24 food record and the image-assisted ASA24 recall will be evaluated only in Module 3. Total energy intake, macronutrient and dietary fiber intake data are the main outcomes for validity testing compared against measures of actual intake. Acceptability will be determined from feedback surveys.
Conditions Studied
Interventions
- OTHER Diet A
- OTHER Diet B
- OTHER Diet C
Study Locations (14)
California
- USDA Western Human Nutrition Research Center - Davis
- University of California, Los Angeles - Los Angeles
- University of California, Davis - Sacramento
- Cedars Sinai Medical Center - West Hollywood
Illinois
- Northwestern University - Chicago
- Illinois Institute of Technology - Chicago
- University of Chicago - Chicago
Louisiana
- Pennington Biomedical Research Center - Baton Rouge
- Louisiana State University Health Sciences Center - New Orleans
Massachusetts
- Tufts University - Boston
- Massachusetts General Hospital - Boston
North Carolina
- University of North Carolina at Chapel Hill - Chapel Hill Clinic - Chapel Hill
- University of North Carolina at Chapel Hill - Kannapolis - Kannapolis
Alabama
- University of Alabama at Birmingham - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8,000 participants |
| Start Date | 2023-04-14 |
| Est. Completion | 2027-01-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05701657
The ClinicalTrials.gov registry entry for NCT05701657 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 8,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 2,845-participant average among 22 other Nutrition trials with a reported enrollment target (181% higher). The listed sponsor is RTI International, which has 45 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Nutrition appearing as the primary indexed condition, and to 3 interventions - of which Diet A is the first listed.
NCT05701657 reports 14 study locations spanning 6 distinct geographic areas - top geographies include California, Illinois, Louisiana.
Frequently Asked Questions
What is clinical trial NCT05701657 about?
NCT05701657 is a clinical study titled "Nutrition for Precision Health, Powered by the All of Us". The goal of this Nutrition for Precision Health (NPH) powered by All of Us research study is to develop Artificial Intelligence/Machine Learning (AI/ML) algorithms that predict individual responses to diet patterns using rich multimodal data streams collected across multiple domains (e.g., behavior,...
What is the current status of trial NCT05701657?
This trial is currently recruiting. It is a NA study. The enrollment target is 8,000 participants. The study started on 2023-04-14. Estimated completion is 2027-01-31.
What conditions does trial NCT05701657 study?
This clinical trial studies the following conditions: Nutrition, Dietary Habits, Health.
What interventions are being tested in trial NCT05701657?
The interventions under investigation include: Diet A (OTHER), Diet B (OTHER), Diet C (OTHER).
Who is sponsoring clinical trial NCT05701657?
This trial is sponsored by RTI International, which has 45 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05701657 being conducted?
This trial has 14 study locations across Alabama, California, Illinois, Louisiana, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Nutrition
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Salud Diabetes: A Pilot Study Comparing Lifestyle Interventions and Real-Time Continuous Glucose Monitoring
RECRUITING · NA
-
Healthy School Recognized Campus: A Hybrid Type 2 Implementation-Effectiveness Trial
RECRUITING · NA
-
Extended Release Protein Dosing
RECRUITING · NA
-
Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters
RECRUITING · NA
-
Strong Teens for Healthy Schools Change Club: A Civic Engagement Approach to Improving Physical Activity and Healthy Eating Environments
RECRUITING · NA
-
Nourish Clinical Trial
RECRUITING · NA
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.