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NCT05699252 · ClinicalTrials.gov registry record · NA
Matching Adults to Treatments for Chronic Pain (MATCH) Study
A NA study of Chronic Pain, sponsored by University of Washington.
- Active
- Registry status
- NA
- Development phase
- 331
- Enrollment target
- 3
- Study locations
NCT05699252 is a NA study of Chronic Pain that is active but no longer recruiting, run by University of Washington. The registered enrollment target is 331 participants, below the 771-participant average among 301 other Chronic Pain trials with a reported enrollment target (57% lower). The trial reports 3 study locations across 1 state.
The verdict
NCT05699252, a NA study of Chronic Pain, is active but no longer recruiting, sponsored by University of Washington.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 331 participants
- Enrollment target
- 3
- Study locations
Study Summary
Chronic pain is a prevalent, disabling problem affecting as many as 50% of men and 75% of women Veterans. Cognitive Behavioral Therapy (CBT) is the current gold standard treatment for chronic pain. However, while some individuals do respond to CBT, many individuals do not obtain meaningful benefit. As a result, the average response to CBT treatment in groups of individuals with chronic pain is only modest. To address the need for effective treatments, the investigators have developed and adapted Complementary and Integrative Health (CIH) interventions such as Mindfulness-Based Cognitive Therapy (MBCT) and Hypnotic Cognitive Therapy (HYP-CT) for chronic pain management. Research shows these treatments are beneficial alternatives to CBT. However, as with CBT, response to these treatments varies, and the investigators' preliminary data suggests outcome variability is explained by a number of baseline patient factors. Research is now needed to advance knowledge regarding the pre-treatment patient factors (i.e., predictive markers) that moderate treatment outcome (i.e., patient factors that interact with treatment condition to predict outcome). The findings from this research will provide an empirical basis for developing patient-treatment matching algorithms to prospectively match a given individual to the evidence-based treatment most likely to be beneficial for them. The investigators have initiated a program of research to identify the factors that predict response to psychosocial pain treatments, including HYP-CT, MBCT, and CBT. Preliminary findings suggest that predictive markers such as brain activity (e.g., alpha and beta power, as measured by EEG), and the traits of mindfulness, hypnotizability, and catastrophizing, will predict who benefits most from different treatments. For example, post hoc analyses show that those who are "well-matched" to HYP-CT, based on the identified baseline moderators, achieve twice the amount of pain reduction with treatment, compa
Conditions Studied
Interventions
- BEHAVIORAL Cognitive Behavioral Therapy (CBT)
- BEHAVIORAL Mindfulness-Based Cognitive Therapy (MBCT)
- BEHAVIORAL Hypnotic Cognitive Therapy (HYP-CT)
Study Locations (3)
Washington
- University of Washington, Ninth and Jefferson Building - Seattle
- VA Puget Sound Health Care System, Seattle Division - Seattle
- VA Puget Sound Health Care System, American Lake - Tacoma
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 331 participants |
| Start Date | 2023-04-26 |
| Est. Completion | 2027-02-28 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05699252
The ClinicalTrials.gov registry entry for NCT05699252 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 331 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 771-participant average among 301 other Chronic Pain trials with a reported enrollment target (57% lower). The listed sponsor is University of Washington, which has 1,048 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Chronic Pain appearing as the primary indexed condition, and to 3 interventions - of which Cognitive Behavioral Therapy (CBT) is the first listed.
NCT05699252 reports 3 study locations spanning 1 distinct geographic area - top geographies include Washington.
Frequently Asked Questions
What is clinical trial NCT05699252 about?
NCT05699252 is a clinical study titled "Matching Adults to Treatments for Chronic Pain (MATCH) Study". Chronic pain is a prevalent, disabling problem affecting as many as 50% of men and 75% of women Veterans. Cognitive Behavioral Therapy (CBT) is the current gold standard treatment for chronic pain. However, while some individuals do respond to CBT, many individuals do not obtain meaningful benefit. ...
What is the current status of trial NCT05699252?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 331 participants. The study started on 2023-04-26. Estimated completion is 2027-02-28.
What conditions does trial NCT05699252 study?
This clinical trial studies the following conditions: Chronic Pain.
What interventions are being tested in trial NCT05699252?
The interventions under investigation include: Cognitive Behavioral Therapy (CBT) (BEHAVIORAL), Mindfulness-Based Cognitive Therapy (MBCT) (BEHAVIORAL), Hypnotic Cognitive Therapy (HYP-CT) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05699252?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05699252 being conducted?
This trial has 3 study locations across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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