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NCT05680740 · ClinicalTrials.gov registry record · Phase 4

A Study to Investigate Efficacy and Safety of VTAMA (Tapinarof) Cream, 1% in Intertriginous Plaque Psoriasis

A Phase 4 study, sponsored by Organon and.

Completed
Registry status
Phase 4
Development phase
34
Enrollment target

NCT05680740: Completed Phase 4 study, sponsored by Organon and.

NCT05680740 is a Phase 4 study that has completed, run by Organon and. The registered enrollment target is 34 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05680740, a Phase 4 study, has completed, sponsored by Organon and.

COMPLETED
Registry status
Phase 4
Development phase
34 participants
Enrollment target

Study Summary

This is an open-label, multi-center study to evaluate the efficacy and safety of VTAMA (tapinarof) cream, 1% in adults with intertriginous psoriasis

Primary Outcome

Intertriginous Physician Global Assessment (iPGA) is a clinical tool for assessing the current state/severity of a subject's psoriasis in the intertriginous areas at a given timepoint. It is a static 5-point assessment of plaque qualities on the clinical characteristics of erythema, scaling, and plaque thickness/elevation within the intertriginous areas. The iPGA ranges from 0 to 4, and is calculated as Clear (0), Almost Clear (1), Mild (2), Moderate (3), and Severe (4). Higher iPGA scores repre

Interventions

  • DRUG VTAMA® (tapinarof) Cream 1%

Trial Details

FieldValue
Enrollment Target 34 participants
Start Date 2022-12-27
Est. Completion 2023-05-25
Phase Phase 4
Organon and

15 total trials

What the finished NCT05680740 record still lists

NCT05680740 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (93% lower).

The record links to 0 conditions, and to 1 intervention - of which VTAMA® (tapinarof) Cream 1% is the first listed.

NCT05680740 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05680740 about?

NCT05680740 is a clinical study titled "A Study to Investigate Efficacy and Safety of VTAMA (Tapinarof) Cream, 1% in Intertriginous Plaque Psoriasis". This is an open-label, multi-center study to evaluate the efficacy and safety of VTAMA (tapinarof) cream, 1% in adults with intertriginous psoriasis

What is the current status of trial NCT05680740?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 34 participants. The study started on 2022-12-27. Estimated completion is 2023-05-25.

What interventions are being tested in trial NCT05680740?

The interventions under investigation include: VTAMA® (tapinarof) Cream 1% (DRUG).

Who is sponsoring clinical trial NCT05680740?

This trial is sponsored by Organon and, which has 15 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05680740's enrollment target sits among peer trials

34 1520th of 2000 higher than 473 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05680740, the US trial registry maintained by the National Library of Medicine. NCT05680740 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.