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NCT05673603 · ClinicalTrials.gov registry record · Phase 1
A Study of Brensocatib Following a Single Oral Administration in Participants With or Without Renal Impairment
A Phase 1 study, sponsored by Insmed Incorporated.
- Completed
- Registry status
- Phase 1
- Development phase
- 28
- Enrollment target
NCT05673603: Completed Phase 1 study, sponsored by Insmed Incorporated.
NCT05673603 is a Phase 1 study that has completed, run by Insmed Incorporated. The registered enrollment target is 28 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05673603, a Phase 1 study, has completed, sponsored by Insmed Incorporated.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 28 participants
- Enrollment target
Study Summary
The primary purpose of the study is to determine the pharmacokinetics (PK) following a single oral dose administration of brensocatib, safety, and tolerability of brensocatib when administered to participants with impaired renal function and in healthy participants.
Primary Outcome
Pharmacokinetics of brensocatib following a single dose will be assessed in participants with renal impairment and in healthy participants.
Interventions
- DRUG Brensocatib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2021-07-20 |
| Est. Completion | 2023-02-14 |
| Phase | Phase 1 |
What the finished NCT05673603 record still lists
NCT05673603 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower).
The record links to 0 conditions, and to 1 intervention - of which Brensocatib is the first listed.
NCT05673603 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05673603 about?
NCT05673603 is a clinical study titled "A Study of Brensocatib Following a Single Oral Administration in Participants With or Without Renal Impairment". The primary purpose of the study is to determine the pharmacokinetics (PK) following a single oral dose administration of brensocatib, safety, and tolerability of brensocatib when administered to participants with impaired renal function and in healthy participants.
What is the current status of trial NCT05673603?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2021-07-20. Estimated completion is 2023-02-14.
What interventions are being tested in trial NCT05673603?
The interventions under investigation include: Brensocatib (DRUG).
Who is sponsoring clinical trial NCT05673603?
This trial is sponsored by Insmed Incorporated, which has 31 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05673603's enrollment target sits among peer trials
28 1447th of 2000 higher than 538 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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