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NCT05651152 · ClinicalTrials.gov registry record · Phase 1
A Study to Investigate The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JZP441 in Sleep-deprived Healthy Participants
A Phase 1 study, sponsored by Jazz Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 105
- Enrollment target
NCT05651152: Completed Phase 1 study, sponsored by Jazz Pharmaceuticals.
NCT05651152 is a Phase 1 study that has completed, run by Jazz Pharmaceuticals. The registered enrollment target is 105 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05651152, a Phase 1 study, has completed, sponsored by Jazz Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 105 participants
- Enrollment target
Study Summary
This Phase 1, double-blind, randomized, placebo-controlled study will characterize the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of ascending nighttime doses of JZP441 in sleep-deprived healthy participants.
Interventions
- DRUG Placebo
- DRUG JZP441
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2022-11-28 |
| Est. Completion | 2023-11-15 |
| Phase | Phase 1 |
What the finished NCT05651152 record still lists
NCT05651152 is an interventional study that assigns participants to a tested intervention. The registered 105 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05651152 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05651152 about?
NCT05651152 is a clinical study titled "A Study to Investigate The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JZP441 in Sleep-deprived Healthy Participants". This Phase 1, double-blind, randomized, placebo-controlled study will characterize the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of ascending nighttime doses of JZP441 in sleep-deprived healthy participants.
What is the current status of trial NCT05651152?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 105 participants. The study started on 2022-11-28. Estimated completion is 2023-11-15.
What interventions are being tested in trial NCT05651152?
The interventions under investigation include: Placebo (DRUG), JZP441 (DRUG).
Who is sponsoring clinical trial NCT05651152?
This trial is sponsored by Jazz Pharmaceuticals, which has 128 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05651152's enrollment target sits among peer trials
105 533rd of 2000 higher than 1,465 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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