Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 2

Letrozole in Uterine Leiomyosarcoma

NCT05649956 · View on ClinicalTrials.gov ↗

Study Summary

This is a clinical trial to test letrozole in patients with uterine leiomyosarcoma. The main question is will treatment with letrozole extend progression-free survival in patients. Patients will receive 2/5 mg of letrozole daily.

Conditions Studied

Interventions

  • DRUG Letrozole

Study Locations (13)

Colorado

  • University of Colorado Cancer Center - Anschutz Cancer Pavilion — Aurora
  • Highlands Ranch Hospital — Highlands Ranch

Nevada

  • Women's Cancer Center of Nevada — Las Vegas
  • Women's Cancer Center of Nevada — Las Vegas

Florida

  • Mount Sinai Comprehensive Cancer Center — Miami Beach

Illinois

  • Endeavor Health - Kellogg Cancer Center — Evanston

Louisiana

  • WK Physician Network-Gynecologic Oncology Associates — Shreveport

Massachusetts

  • University of Massachusetts Memorial Medical Center — Worcester

New Mexico

  • University of New Mexico Comprehensive Cancer Center — Albuquerque

North Carolina

  • East Carolina University Health Medical Center — Greenville

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2024-07-17
Est. Completion 2029-07-30
Phase Phase 2

Sponsor

GOG Foundation

37 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05649956

The ClinicalTrials.gov registry entry for NCT05649956 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GOG Foundation, which has 37 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Uterine Leiomyosarcoma appearing as the primary indexed condition, and to 1 intervention — of which Letrozole is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05649956 reports 13 study locations spanning 11 distinct geographic areas — top geographies include Colorado, Nevada, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05649956 about?

NCT05649956 is a clinical study titled "Letrozole in Uterine Leiomyosarcoma". This is a clinical trial to test letrozole in patients with uterine leiomyosarcoma. The main question is will treatment with letrozole extend progression-free survival in patients. Patients will receive 2/5 mg of letrozole daily.

What is the current status of trial NCT05649956?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2024-07-17. Estimated completion is 2029-07-30.

What conditions does trial NCT05649956 study?

This clinical trial studies the following conditions: Uterine Leiomyosarcoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05649956?

The interventions under investigation include: Letrozole (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05649956?

This trial is sponsored by GOG Foundation, which has 37 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05649956 being conducted?

This trial has 13 study locations across Colorado, Florida, Illinois, Louisiana, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial