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NCT05642026 · ClinicalTrials.gov registry record · Phase 4

INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures

A Phase 4 study of Rib Fractures, sponsored by Zachary Warriner.

Recruiting
Registry status
Phase 4
Development phase
180
Enrollment target
1
Study location

NCT05642026: Recruiting Phase 4 study of Rib Fractures, sponsored by Zachary Warriner.

NCT05642026 is a Phase 4 study of Rib Fractures that is actively recruiting participants, run by Zachary Warriner. The registered enrollment target is 180 participants, above the 81-participant average among 9 other Rib Fractures trials with a reported enrollment target (122% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05642026, a Phase 4 study of Rib Fractures, is actively recruiting participants, sponsored by Zachary Warriner.

RECRUITING
Registry status
Phase 4
Development phase
180 participants
Enrollment target
1
Study location

Study Summary

This is a prospective, randomized, non-blinded study comparing CINB plus medical therapy versus standard medical care (non-steroidals and opioids intravenous/oral inpatient and oral outpatient) alone for patients with multiple rib fractures. The objective of this study is to analyze the effect of continuous intercostal nerve block (CINB) in the treatment of patients admitted to the adult trauma service with rib fractures. The effectiveness of CINB as adjunctive treatment will be compared to standard medical therapy involving nonsteroidal and intravenous/oral opioid medications.

Primary Outcome

time from randomization until the time of discharge

Conditions Studied

Interventions

  • DRUG Ropivacaine
  • DRUG Non steroidal anti-inflammatory drug and opioids

Study Locations (1)

Kentucky

  • University of Kentucky Medical Center - Lexington

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2025-09-23
Est. Completion 2027-02-01
Phase Phase 4
Zachary Warriner

1 total trials

What NCT05642026 shows while recruiting

NCT05642026 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, above the 81-participant average among 9 other Rib Fractures trials with a reported enrollment target (122% higher).

The record links to 1 condition, with Rib Fractures appearing as the primary indexed condition, and to 2 interventions - of which Ropivacaine is the first listed.

NCT05642026 reports a single indexed study location in Kentucky.

Frequently Asked Questions

What is clinical trial NCT05642026 about?

NCT05642026 is a clinical study titled "INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures". This is a prospective, randomized, non-blinded study comparing CINB plus medical therapy versus standard medical care (non-steroidals and opioids intravenous/oral inpatient and oral outpatient) alone for patients with multiple rib fractures. The objective of this study is to analyze the effect of co...

What is the current status of trial NCT05642026?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 180 participants. The study started on 2025-09-23. Estimated completion is 2027-02-01.

What conditions does trial NCT05642026 study?

This clinical trial studies the following conditions: Rib Fractures.

What interventions are being tested in trial NCT05642026?

The interventions under investigation include: Ropivacaine (DRUG), Non steroidal anti-inflammatory drug and opioids (DRUG).

Who is sponsoring clinical trial NCT05642026?

This trial is sponsored by Zachary Warriner, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05642026 being conducted?

This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Rib Fractures

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05642026's enrollment target sits among peer trials

180 2nd of 9 the highest of 9 other Rib Fractures trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Rib Fractures trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05642026, the US trial registry maintained by the National Library of Medicine. NCT05642026 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.