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NCT05616234 · ClinicalTrials.gov registry record · NA
Exercise-induced Changes in Exosomes
A NA study, sponsored by University of California, Davis.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
NCT05616234 is a NA study that has completed, run by University of California, Davis. The registered enrollment target is 12 participants.
The verdict
NCT05616234, a NA study, has completed, sponsored by University of California, Davis.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
Study Summary
The proposed study aims to shed light on the function/importance/relevance of exercise-induced changes in exosomes to connective tissues. Exosomes are known to increase robustly in response to exercise. We have previously shown that serum isolated from subjects after they lift heavy weights increases human engineered ligament collagen content and mechanics more than serum from before they lift weight. Further, we showed that exercise-induced changes in hormones could not explain the change in ligament structure or function. These data indicate that there is a significant gap in our understanding of muscle-connective tissue crosstalk. To address this gap, the current proposal seeks to: i) isolate and sequence exosomal RNA (long non-coding, miR, and mRNA) and ii) determine whether exosomes isolated from serum after exercise increase engineered ligament mechanics and collagen content.
Interventions
- PROCEDURE Resistance Exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2022-11-07 |
| Est. Completion | 2023-02-17 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05616234
The ClinicalTrials.gov registry entry for NCT05616234 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Resistance Exercise is the first listed.
NCT05616234 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05616234 about?
NCT05616234 is a clinical study titled "Exercise-induced Changes in Exosomes". The proposed study aims to shed light on the function/importance/relevance of exercise-induced changes in exosomes to connective tissues. Exosomes are known to increase robustly in response to exercise. We have previously shown that serum isolated from subjects after they lift heavy weights increase...
What is the current status of trial NCT05616234?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2022-11-07. Estimated completion is 2023-02-17.
What interventions are being tested in trial NCT05616234?
The interventions under investigation include: Resistance Exercise (PROCEDURE).
Who is sponsoring clinical trial NCT05616234?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
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