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NCT05616130 · ClinicalTrials.gov registry record
Pathological Myeloid Activation After Sepsis and Trauma
A clinical trial of Sepsis and Trauma Injury, sponsored by University of Florida.
- Recruiting
- Registry status
- 255
- Enrollment target
- 1
- Study location
NCT05616130 is a study of Sepsis and Trauma Injury that is actively recruiting participants, run by University of Florida. The registered enrollment target is 255 participants, below the 6,562-participant average among 90 other Sepsis trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05616130, a study of Sepsis and Trauma Injury, is actively recruiting participants, sponsored by University of Florida.
- RECRUITING
- Registry status
- 255 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this observational study is to better understand what happens to circulating blood after a patient experiences severe trauma injury. The main questions it aims to answer are: Is severe human trauma associated with specific patterns of development in the hematopoietic stem cells of these patients? and Does the initial severe trauma injury create immunosuppression and increase risk of in-hospital sepsis? Participants in study will give blood samples and a waste sample of bone marrow at time of operative repair of traumatic orthopedic injuries, supply medical information and participate in surveys and assessments during recovery from their injury(ies). Researchers will compare severe trauma injury patients to elective hip repair patients to see if immunosuppression and specific development patterns occur in the trauma patient versus the otherwise healthy hip surgery patient.
Conditions Studied
Interventions
- OTHER Data Collection
- PROCEDURE Bone marrow collection and blood collection
- OTHER Serial interviews to complete surveys and questionnaires
- OTHER Telephone follow up call
Study Locations (1)
Florida
- UF Health at Shands Hospital - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 255 participants |
| Start Date | 2022-09-01 |
| Est. Completion | 2028-09-30 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05616130
The ClinicalTrials.gov registry entry for NCT05616130 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 255 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 6,562-participant average among 90 other Sepsis trials with a reported enrollment target (96% lower). The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Sepsis appearing as the primary indexed condition, and to 4 interventions - of which Data Collection is the first listed.
NCT05616130 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.
Frequently Asked Questions
What is clinical trial NCT05616130 about?
NCT05616130 is a clinical study titled "Pathological Myeloid Activation After Sepsis and Trauma". The goal of this observational study is to better understand what happens to circulating blood after a patient experiences severe trauma injury. The main questions it aims to answer are: Is severe human trauma associated with specific patterns of development in the hematopoietic stem cells of these ...
What is the current status of trial NCT05616130?
This trial is currently recruiting. The enrollment target is 255 participants. The study started on 2022-09-01. Estimated completion is 2028-09-30.
What conditions does trial NCT05616130 study?
This clinical trial studies the following conditions: Sepsis, Trauma Injury, Immunosuppression, Chronic Critical Illness.
What interventions are being tested in trial NCT05616130?
The interventions under investigation include: Data Collection (OTHER), Bone marrow collection and blood collection (PROCEDURE), Serial interviews to complete surveys and questionnaires (OTHER), Telephone follow up call (OTHER).
Who is sponsoring clinical trial NCT05616130?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05616130 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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