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NCT05551949 · ClinicalTrials.gov registry record · Phase 4
Preventing Recurrent UTI With Vaginal Estrogen
A Phase 4 study, sponsored by Johns Hopkins University.
- Completed
- Registry status
- Phase 4
- Development phase
- 27
- Enrollment target
NCT05551949: Completed Phase 4 study, sponsored by Johns Hopkins University.
NCT05551949 is a Phase 4 study that has completed, run by Johns Hopkins University. The registered enrollment target is 27 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05551949, a Phase 4 study, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 27 participants
- Enrollment target
Study Summary
Among postmenopausal women who suffer from recurrent urinary tract infections (UTI), vaginal estrogen therapy prevents UTI recurrences for 50% of sufferers. This research will investigate why some women benefit but others do not, focusing on (a) the effects of vaginal estrogen therapy on the bacteria that inhabit the vagina and bladder, (b) its influence on immune responses in both compartments, and (c) the extent to which those changes are critical to successful UTI prevention. The findings will be a first step in the development of more effective strategies to prevent UTI, one of the most common and costly benign urologic conditions.
Interventions
- DRUG Vaginal estradiol tablets
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2022-01-01 |
| Est. Completion | 2025-08-31 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05551949
The ClinicalTrials.gov registry entry for NCT05551949 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 27 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Vaginal estradiol tablets is the first listed.
NCT05551949 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05551949 about?
NCT05551949 is a clinical study titled "Preventing Recurrent UTI With Vaginal Estrogen". Among postmenopausal women who suffer from recurrent urinary tract infections (UTI), vaginal estrogen therapy prevents UTI recurrences for 50% of sufferers. This research will investigate why some women benefit but others do not, focusing on (a) the effects of vaginal estrogen therapy on the bacteri...
What is the current status of trial NCT05551949?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 27 participants. The study started on 2022-01-01. Estimated completion is 2025-08-31.
What interventions are being tested in trial NCT05551949?
The interventions under investigation include: Vaginal estradiol tablets (DRUG).
Who is sponsoring clinical trial NCT05551949?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
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