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NCT05529849 · ClinicalTrials.gov registry record · Phase 1
A Study to Assess the Safety, Tolerability and Pharmacokinetics of TCMCB07 in Single and Multiple Ascending Doses in Health Subjects
A Phase 1 study, sponsored by Endevica Bio.
- Completed
- Registry status
- Phase 1
- Development phase
- 76
- Enrollment target
NCT05529849: Completed Phase 1 study, sponsored by Endevica Bio.
NCT05529849 is a Phase 1 study that has completed, run by Endevica Bio. The registered enrollment target is 76 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05529849, a Phase 1 study, has completed, sponsored by Endevica Bio.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 76 participants
- Enrollment target
Study Summary
This study will test an experimental drug named TCMCB07 for the treatment of cancer cachexia. Cachexia is a syndrome characterized by weight loss, anorexia, weakness or lack of energy, and anemia. Cachexia occurs in many cancers, usually at the advanced stages of disease.
Primary Outcome
Adverse Event monitoring
Interventions
- DRUG Placebo
- DRUG TCMCB07
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 76 participants |
| Start Date | 2022-07-12 |
| Est. Completion | 2023-02-20 |
| Phase | Phase 1 |
What the finished NCT05529849 record still lists
NCT05529849 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05529849 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05529849 about?
NCT05529849 is a clinical study titled "A Study to Assess the Safety, Tolerability and Pharmacokinetics of TCMCB07 in Single and Multiple Ascending Doses in Health Subjects". This study will test an experimental drug named TCMCB07 for the treatment of cancer cachexia. Cachexia is a syndrome characterized by weight loss, anorexia, weakness or lack of energy, and anemia. Cachexia occurs in many cancers, usually at the advanced stages of disease.
What is the current status of trial NCT05529849?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 76 participants. The study started on 2022-07-12. Estimated completion is 2023-02-20.
What interventions are being tested in trial NCT05529849?
The interventions under investigation include: Placebo (DRUG), TCMCB07 (DRUG).
Who is sponsoring clinical trial NCT05529849?
This trial is sponsored by Endevica Bio, which has 2 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05529849's enrollment target sits among peer trials
76 705th of 2000 higher than 1,290 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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