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NCT05529173 · ClinicalTrials.gov registry record · Phase 4
Povidone-Iodine for Nasal Decolonization
A Phase 4 study, sponsored by Rutgers, The State University of New Jersey.
- Completed
- Registry status
- Phase 4
- Development phase
- 192
- Enrollment target
NCT05529173: Completed Phase 4 study, sponsored by Rutgers, The State University of New Jersey.
NCT05529173 is a Phase 4 study that has completed, run by Rutgers, The State University of New Jersey. The registered enrollment target is 192 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (63% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05529173, a Phase 4 study, has completed, sponsored by Rutgers, The State University of New Jersey.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 192 participants
- Enrollment target
Study Summary
To evaluate the efficacy and tolerability of 10% povidone-iodine in eliminating nasal carriage of Staphylococcus aureus and MRSA. To determine whether a more convenient, single-dose, pre-operative 10% povidone-iodine (PI) application is effective in reducing nasal carriage of S. aureus and MRSA. We expect a statistically significant decrease in S. aureus/MRSA colonization in nasal cultures taken perioperatively after intervention in patients who received pretreatment with PI as compared to patients who received normal saline (NS).
Primary Outcome
The difference in a number of S. aureus/MRSA CFU in nasal swab specimens between before and after the study drug/placebo application in patients with a positive for S. aureus/MRSA pre-interventional nasal swab specimen. The change (Δ) is calculated as the value at the baseline time point minus the value at the later time point. Positive values represent a decrease in CFU, whereas negative values represent an increase in CFU.
Interventions
- DRUG Povidone-Iodine 10%
- DRUG 0.9% NaCl Solution
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 192 participants |
| Start Date | 2022-09-06 |
| Est. Completion | 2023-11-17 |
| Phase | Phase 4 |
What the finished NCT05529173 record still lists
NCT05529173 is an interventional study that assigns participants to a tested intervention. The registered 192 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (63% lower).
The record links to 0 conditions, and to 2 interventions - of which Povidone-Iodine 10% is the first listed.
NCT05529173 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05529173 about?
NCT05529173 is a clinical study titled "Povidone-Iodine for Nasal Decolonization". To evaluate the efficacy and tolerability of 10% povidone-iodine in eliminating nasal carriage of Staphylococcus aureus and MRSA. To determine whether a more convenient, single-dose, pre-operative 10% povidone-iodine (PI) application is effective in reducing nasal carriage of S. aureus and MRSA. We ...
What is the current status of trial NCT05529173?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 192 participants. The study started on 2022-09-06. Estimated completion is 2023-11-17.
What interventions are being tested in trial NCT05529173?
The interventions under investigation include: Povidone-Iodine 10% (DRUG), 0.9% NaCl Solution (DRUG).
Who is sponsoring clinical trial NCT05529173?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05529173's enrollment target sits among peer trials
192 451st of 2000 higher than 1,548 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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