Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05525494 · ClinicalTrials.gov registry record · NA
Patient Portal Flu Vaccine Reminders (5)
A NA study, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- NA
- Development phase
- 262,085
- Enrollment target
NCT05525494: Completed NA study, sponsored by University of California, Los Angeles.
NCT05525494 is a NA study that has completed, run by University of California, Los Angeles. The registered enrollment target is 262,085 participants, above the 1,399-participant average among 58,714 other NA trials with a reported enrollment target (18634% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05525494, a NA study, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- NA
- Development phase
- 262,085 participants
- Enrollment target
Study Summary
This trial is taking place in Los Angeles, CA at clinics within the UCLA Health System. The study design is a 2x2 nested factorial design. Patients will be randomized into 1) receiving text based reminder messages with direct scheduling link, 2) portal-based reminder messages with direct scheduling link, or 3) the control group. Patients randomized to the intervention arms will receive reminders if they are due for influenza vaccine. Nested within the portal reminder arm, we will have two additional components for which patients will be randomized separately: 1. A pre-commitment prompt, asking patients which time (September, October, November or December) and which place (UCLA, pharmacy, workplace or school, or other) they plan to get their Influenza vaccine with tailored monthly messages based on responses (pre-commitment message with tailored recall messages with direct scheduling vs. standard portal reminders with direct scheduling). 2. A pre-appointment reminder encouraging patients to ask for their influenza vaccine at their upcoming appointment (pre-appointment reminder encouraging influenza vaccination vs. standard pre-appointment reminder not mentioning influenza vaccination) Nested within the text message reminder arm, we will have one additional component for which patients will be randomized separately: 1\) A pre-appointment reminder encouraging patients to ask for their influenza vaccine at their upcoming appointment (pre-appointment reminder encouraging influenza vaccination vs. standard pre-appointment reminder not mentioning influenza vaccination) Despite the Advisory Committee on Immunization Practices (ACIP) recommendation in 2010 that all people above 6 months of age should receive an annual flu vaccine, vaccination rates remain low: at 6m-4.9 yrs. (70%), 5-17.9 yrs. (56%), 18-64.9 yrs. (38%), and \>65 yrs. (63%). The investigators will assess the effectiveness of MyChart R/R messages and text R/R messages as compared to the standard of care
Primary Outcome
Percent of patients with annual influenza vaccination (between 9/1/22 - 4/1/23) among index patients. Outcomes will be assessed via vaccine data extraction from the electronic health record and external claims and pharmacy data. The index patients must also be an active UCLA Health MyChart user (\>= 1 login over the last 12 months from 8/1/22, excluding activity on the user's initial profile activation date). Individuals not affiliated with any primary care practice will be excluded from the pr
Interventions
- BEHAVIORAL Text Fixed R/R Messages with Direct Appointment Schedule Link
- BEHAVIORAL Text Pre-Appointment Reminder
- BEHAVIORAL Portal Pre-Commitment Prompt with Tailored R/R Messages with Direct Appointment Schedule Link
- BEHAVIORAL Portal Fixed R/R Messages with Direct Appointment Schedule Link
- BEHAVIORAL Portal Pre-Appointment Reminder
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 262,085 participants |
| Start Date | 2022-09-07 |
| Est. Completion | 2023-04-01 |
| Phase | NA |
What the finished NCT05525494 record still lists
NCT05525494 is an interventional study that assigns participants to a tested intervention. Its 262,085 participants enrollment target places it among the larger protocols in the corpus, above the 1,399-participant average among 58,714 other NA trials with a reported enrollment target (18634% higher).
The record links to 0 conditions, and to 5 interventions - of which Text Fixed R/R Messages with Direct Appointment Schedule Link is the first listed.
NCT05525494 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05525494 about?
NCT05525494 is a clinical study titled "Patient Portal Flu Vaccine Reminders (5)". This trial is taking place in Los Angeles, CA at clinics within the UCLA Health System. The study design is a 2x2 nested factorial design. Patients will be randomized into 1) receiving text based reminder messages with direct scheduling link, 2) portal-based reminder messages with direct scheduling...
What is the current status of trial NCT05525494?
This trial is currently completed. It is a NA study. The enrollment target is 262,085 participants. The study started on 2022-09-07. Estimated completion is 2023-04-01.
What interventions are being tested in trial NCT05525494?
The interventions under investigation include: Text Fixed R/R Messages with Direct Appointment Schedule Link (BEHAVIORAL), Text Pre-Appointment Reminder (BEHAVIORAL), Portal Pre-Commitment Prompt with Tailored R/R Messages with Direct Appointment Schedule Link (BEHAVIORAL), Portal Fixed R/R Messages with Direct Appointment Schedule Link (BEHAVIORAL), Portal Pre-Appointment Reminder (BEHAVIORAL).
Who is sponsoring clinical trial NCT05525494?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05525494's enrollment target sits among peer trials
262,085 1st of 2000 higher than 2,000 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04735835 · 250,000 participants · NA
Personalized Responses to Dietary Composition Trial 3
- NCT02280733 · 300,000 participants
A Real-World Registry of Chronic Wounds and Ulcers
- NCT06694181 · 300,000 participants
Safe and Explainable AI
- NCT07314697 · 300,000 participants · NA
Arrival Time Implementation
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI