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NCT05517837 · ClinicalTrials.gov registry record · Early Phase 1

A Phase 1, First-in-Human Study of BMS-986421 in Healthy Participants

A Early Phase 1 study, sponsored by Bristol-Myers Squibb.

Terminated
Registry status
Early Phase 1
Development phase
46
Enrollment target

NCT05517837: Clinical Trial Early Phase 1 study, sponsored by Bristol-Myers Squibb.

NCT05517837 is a Early Phase 1 study that was terminated before completion, run by Bristol-Myers Squibb. The registered enrollment target is 46 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (13% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05517837, a Early Phase 1 study, was terminated before completion, sponsored by Bristol-Myers Squibb.

TERMINATED
Registry status
Early Phase 1
Development phase
46 participants
Enrollment target

Study Summary

The purpose of this study is to assess the safety and tolerability of BMS-986421 in healthy adult participants.

Interventions

  • OTHER Placebo
  • DRUG BMS-986421

Trial Details

FieldValue
Enrollment Target 46 participants
Start Date 2022-09-13
Est. Completion 2023-07-14
Phase Early Phase 1
Bristol-Myers Squibb

1,025 total trials

Why NCT05517837 stopped before completion

NCT05517837 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (13% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT05517837 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05517837 about?

NCT05517837 is a clinical study titled "A Phase 1, First-in-Human Study of BMS-986421 in Healthy Participants". The purpose of this study is to assess the safety and tolerability of BMS-986421 in healthy adult participants.

What is the current status of trial NCT05517837?

This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 46 participants. The study started on 2022-09-13. Estimated completion is 2023-07-14.

What interventions are being tested in trial NCT05517837?

The interventions under investigation include: Placebo (OTHER), BMS-986421 (DRUG).

Who is sponsoring clinical trial NCT05517837?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05517837's enrollment target sits among peer trials

46 566th of 2000 higher than 1,426 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05517837, the US trial registry maintained by the National Library of Medicine. NCT05517837 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.