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NCT05484882 · ClinicalTrials.gov registry record
Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST): Prospective COVID-19 Natural History Study
A clinical trial, sponsored by National Human Genome Research Institute (NHGRI).
- Completed
- Registry status
- 431
- Enrollment target
NCT05484882: Completed study, sponsored by National Human Genome Research Institute (NHGRI).
NCT05484882 is a clinical trial that has completed, run by National Human Genome Research Institute (NHGRI). The registered enrollment target is 431 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05484882 has completed, sponsored by National Human Genome Research Institute (NHGRI).
- COMPLETED
- Registry status
- 431 participants
- Enrollment target
Study Summary
Background: The COVID-19 pandemic infected and killed African Americans at higher rates than other Americans. Researchers want to understand why. Objective: This natural history study will look at how genetic, environmental, and social factors may predict or affect COVID-19 in African Americans. Information from this study will be combined with data from the GENE-FORECAST study. Eligibility: African Americans who were previously enrolled in GENE-FORECAST. Design: The study includes a telephone interview and 1 visit to the NIH clinic. Participants may engage in either one or both of these activities. The telephone interview will last 20 minutes. Participants will talk about their experiences during the COVID-19 pandemic. The clinic visit will last up to 4 hours. Participants will have a physical exam. They will have blood and urine tests. They will be tested for COVID-19. A long swab will be inserted into a nostril to get a fluid sample from the back of the nose. They will have noninvasive tests of their blood vessels. One device used is a pen-like probe placed lightly on the wrist. Another is a rubber sleeve placed around a finger while a blood pressure cuff is used on the arm. Participants will have a test to measure the electrical activity in their heart. Stickers attached to wires will be placed on their chest, arms, and legs. Participants will answer more questions about COVID-19. They will talk about their health behavior. They will talk about their family's health and the neighborhood they live in. Other questions will ask how they feel, live, work, and play.
Primary Outcome
Vascular function (e.g., pulse wave velocity; vascular stiffness indices; reactive hyperemia)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 431 participants |
| Start Date | 2023-02-18 |
| Est. Completion | 2023-06-26 |
What the finished NCT05484882 record still lists
NCT05484882 is an observational study that tracks outcomes without assigning an intervention. The registered 431 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT05484882 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05484882 about?
NCT05484882 is a clinical study titled "Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST): Prospective COVID-19 Natural History Study". Background: The COVID-19 pandemic infected and killed African Americans at higher rates than other Americans. Researchers want to understand why. Objective: This natural history study will look at how genetic, environmental, and social factors may predict or affect COVID-19 in African Americans. ...
What is the current status of trial NCT05484882?
This trial is currently completed. The enrollment target is 431 participants. The study started on 2023-02-18. Estimated completion is 2023-06-26.
Who is sponsoring clinical trial NCT05484882?
This trial is sponsored by National Human Genome Research Institute (NHGRI), which has 185 total clinical trials registered on ClinicalTrials.gov.
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