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RECRUITING

Natural History Study for DNA Repair Disorders

NCT05484570 · View on ClinicalTrials.gov ↗

Study Summary

This will be a single-center, single-arm, non-interventional natural history study to evaluate the longitudinal clinical course, functional outcome measures, and candidate biomarkers for individuals with DNA repair disorders, including Cockayne syndrome (CS), xeroderma pigmentosum (XP), and trichothiodystrophy (TTD).

Interventions

  • OTHER Interval History
  • OTHER Physical Examination
  • OTHER ECAB Assessment
  • OTHER Gait Assessment
  • OTHER Specimen Sample Collection

Study Locations (1)

Minnesota

  • University of Minnesota- Twin Cities — Minneapolis

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2022-10-01
Est. Completion 2026-12-31

Sponsor

University of Minnesota

919 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05484570

The ClinicalTrials.gov registry entry for NCT05484570 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Minnesota, which has 919 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with DNA Repair Disorder appearing as the primary indexed condition, and to 5 interventions — of which Interval History is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05484570 reports 1 study location spanning 1 distinct geographic area — top geographies include Minnesota. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05484570 about?

NCT05484570 is a clinical study titled "Natural History Study for DNA Repair Disorders". This will be a single-center, single-arm, non-interventional natural history study to evaluate the longitudinal clinical course, functional outcome measures, and candidate biomarkers for individuals with DNA repair disorders, including Cockayne syndrome (CS), xeroderma pigmentosum (XP), and trichoth...

What is the current status of trial NCT05484570?

This trial is currently recruiting. The enrollment target is 40 participants. The study started on 2022-10-01. Estimated completion is 2026-12-31.

What conditions does trial NCT05484570 study?

This clinical trial studies the following conditions: DNA Repair Disorder, Cockayne Syndrome, Xeroderma Pigmentosum, Trichothiodystrophy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05484570?

The interventions under investigation include: Interval History (OTHER), Physical Examination (OTHER), ECAB Assessment (OTHER), Gait Assessment (OTHER), Specimen Sample Collection (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05484570?

This trial is sponsored by University of Minnesota, which has 919 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05484570 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial