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NCT05482113 · ClinicalTrials.gov registry record · Phase 4
Measuring Opioid Use After Rotator Cuff Repair: Comparing the Effects of Standard vs. Extended-release Nerve Blocks
A Phase 4 study, sponsored by Carilion Clinic.
- Completed
- Registry status
- Phase 4
- Development phase
- 17
- Enrollment target
NCT05482113: Completed Phase 4 study, sponsored by Carilion Clinic.
NCT05482113 is a Phase 4 study that has completed, run by Carilion Clinic. The registered enrollment target is 17 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05482113, a Phase 4 study, has completed, sponsored by Carilion Clinic.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 17 participants
- Enrollment target
Study Summary
The investigators aim to determine if a longer acting nerve block, which is a local anesthetic, can help reduce opioid use after surgery in patients that are getting rotator cuff repair surgery. The investigators will also determine if the longer acting block can reduce the number of days that opioids are taken after surgery. Patients that schedule this type of surgery will be given information regarding the study and asked if they want to participate. If they do, they will be randomized to either receive the standard nerve block or the longer acting nerve block. Participants and physicians will not know which nerve block the participants are receiving. Participants will receive a standard pain medication prescription after surgery and will be asked to record pain scores, medications taken and satisfaction level every day in a journal for two weeks. Participants will be asked to bring in their medication bottles and pain journal to the 2-week follow up appointment. Participants' pain scores will be assessed in the office at the follow up appointment and study staff will conduct a pill count. Participants will return for a 6-week follow up appointment and pain scores will be assessed again at that time, and another pill count will be conducted. At this point the study will be complete.
Primary Outcome
Total opioid pills consumed, converted to milligram of morphine equivalents (MME)
Interventions
- DRUG Liposomal bupivacaine
- DRUG Bupivacaine Hcl 0.25% Inj
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2021-03-09 |
| Est. Completion | 2021-12-15 |
| Phase | Phase 4 |
What the finished NCT05482113 record still lists
NCT05482113 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Liposomal bupivacaine is the first listed.
NCT05482113 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05482113 about?
NCT05482113 is a clinical study titled "Measuring Opioid Use After Rotator Cuff Repair: Comparing the Effects of Standard vs. Extended-release Nerve Blocks". The investigators aim to determine if a longer acting nerve block, which is a local anesthetic, can help reduce opioid use after surgery in patients that are getting rotator cuff repair surgery. The investigators will also determine if the longer acting block can reduce the number of days that opioi...
What is the current status of trial NCT05482113?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 17 participants. The study started on 2021-03-09. Estimated completion is 2021-12-15.
What interventions are being tested in trial NCT05482113?
The interventions under investigation include: Liposomal bupivacaine (DRUG), Bupivacaine Hcl 0.25% Inj (DRUG).
Who is sponsoring clinical trial NCT05482113?
This trial is sponsored by Carilion Clinic, which has 45 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05482113's enrollment target sits among peer trials
17 1854th of 2000 higher than 132 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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