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NCT05478772 · ClinicalTrials.gov registry record · Phase 1
Study to Evaluate Multiple Doses of Fluconazole, a CYP3A4 and CYP2C9 Inhibitor, on the Pharmacokinetics of CTP-543 in Healthy Subjects
A Phase 1 study, sponsored by Concert Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
NCT05478772: Completed Phase 1 study, sponsored by Concert Pharmaceuticals.
NCT05478772 is a Phase 1 study that has completed, run by Concert Pharmaceuticals. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05478772, a Phase 1 study, has completed, sponsored by Concert Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
Study Summary
A single center, Phase 1, open-label, fixed-sequence, drug-drug interaction study to evaluate the effect of multiple doses of Fluconazole, a CYP3A4 and CYP2C9 inhibitor, on the pharmacokinetics (PK) of CTP-543 in healthy subjects
Primary Outcome
Maximum observed concentration
Interventions
- DRUG Fluconazole
- DRUG CTP-543
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2022-07-11 |
| Est. Completion | 2022-08-12 |
| Phase | Phase 1 |
What the finished NCT05478772 record still lists
NCT05478772 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 2 interventions - of which Fluconazole is the first listed.
NCT05478772 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05478772 about?
NCT05478772 is a clinical study titled "Study to Evaluate Multiple Doses of Fluconazole, a CYP3A4 and CYP2C9 Inhibitor, on the Pharmacokinetics of CTP-543 in Healthy Subjects". A single center, Phase 1, open-label, fixed-sequence, drug-drug interaction study to evaluate the effect of multiple doses of Fluconazole, a CYP3A4 and CYP2C9 inhibitor, on the pharmacokinetics (PK) of CTP-543 in healthy subjects
What is the current status of trial NCT05478772?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2022-07-11. Estimated completion is 2022-08-12.
What interventions are being tested in trial NCT05478772?
The interventions under investigation include: Fluconazole (DRUG), CTP-543 (DRUG).
Who is sponsoring clinical trial NCT05478772?
This trial is sponsored by Concert Pharmaceuticals, which has 24 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05478772's enrollment target sits among peer trials
18 1720th of 2000 higher than 216 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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