Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05477108 · ClinicalTrials.gov registry record · Phase 1

Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI With Next-Generation Propellant Compared With BGF MDI With HFA Propellant

A Phase 1 study, sponsored by AstraZeneca.

Completed
Registry status
Phase 1
Development phase
108
Enrollment target

NCT05477108 is a Phase 1 study that has completed, run by AstraZeneca. The registered enrollment target is 108 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05477108, a Phase 1 study, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 1
Development phase
108 participants
Enrollment target

Study Summary

The study will assess the Pharmacokinetic (PK) and safety of BGF MDI \[Budesonide/glycopyrronium/formoterol (BGF) metered dose inhaler (MDI)\] formulated with 2 different propellants :Hydrofluoroolefin (HFO) and Hydrofluoroalkane (HFA) with oral activated charcoal in healthy subjects (male or female).

Interventions

  • DRUG Treatment A (BGF MDI HFO with oral activated charcoal)
  • DRUG Treatment B (BGF MDI HFA with oral activated charcoal)

Trial Details

FieldValue
Enrollment Target 108 participants
Start Date 2022-07-29
Est. Completion 2023-04-11
Phase Phase 1

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT05477108

The ClinicalTrials.gov registry entry for NCT05477108 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 108 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Treatment A (BGF MDI HFO with oral activated charcoal) is the first listed.

NCT05477108 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05477108 about?

NCT05477108 is a clinical study titled "Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI With Next-Generation Propellant Compared With BGF MDI With HFA Propellant". The study will assess the Pharmacokinetic (PK) and safety of BGF MDI \[Budesonide/glycopyrronium/formoterol (BGF) metered dose inhaler (MDI)\] formulated with 2 different propellants :Hydrofluoroolefin (HFO) and Hydrofluoroalkane (HFA) with oral activated charcoal in healthy subjects (male or female...

What is the current status of trial NCT05477108?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 108 participants. The study started on 2022-07-29. Estimated completion is 2023-04-11.

What interventions are being tested in trial NCT05477108?

The interventions under investigation include: Treatment A (BGF MDI HFO with oral activated charcoal) (DRUG), Treatment B (BGF MDI HFA with oral activated charcoal) (DRUG).

Who is sponsoring clinical trial NCT05477108?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.