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NCT05470517 · ClinicalTrials.gov registry record · Phase 2
Antibiotic Instillation in Appendicitis
A Phase 2 study, sponsored by Johns Hopkins All Children's Hospital.
- Completed
- Registry status
- Phase 2
- Development phase
- 190
- Enrollment target
NCT05470517 is a Phase 2 study that has completed, run by Johns Hopkins All Children's Hospital. The registered enrollment target is 190 participants.
The verdict
NCT05470517, a Phase 2 study, has completed, sponsored by Johns Hopkins All Children's Hospital.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 190 participants
- Enrollment target
Study Summary
Appendicitis (inflammation of the wall of the appendix, causing pain and tenderness in the abdomen) has a range of severity that goes from simple to complicated. Complicated appendicitis may present with infected fluid inside of the abdomen or a perforation or hole in the intestines. This research is being done to determine if placing an antibiotic solution in the abdomen at the time the appendix is removed is a safe procedure in patients between the ages of 3 and 18 years old with findings of complicated appendicitis. Johns Hopkins All Children's Hospital (JHACH)'s current standard of care for patients with complicated appendicitis includes suctioning the infected fluid out of the abdomen at the time the appendix is removed. As part of this study, the investigators would like to see if patients with complicated appendicitis will benefit from routine care plus leaving an antibiotic solution inside the abdomen, after fully suctioning the infected fluid out of the abdomen.
Interventions
- DRUG Ceftriaxone
- PROCEDURE Intra-peritoneal Fluid Aspiration
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 190 participants |
| Start Date | 2023-01-05 |
| Est. Completion | 2024-03-20 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05470517
The ClinicalTrials.gov registry entry for NCT05470517 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 190 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins All Children's Hospital, which has 24 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Ceftriaxone is the first listed.
NCT05470517 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05470517 about?
NCT05470517 is a clinical study titled "Antibiotic Instillation in Appendicitis". Appendicitis (inflammation of the wall of the appendix, causing pain and tenderness in the abdomen) has a range of severity that goes from simple to complicated. Complicated appendicitis may present with infected fluid inside of the abdomen or a perforation or hole in the intestines. This research ...
What is the current status of trial NCT05470517?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 190 participants. The study started on 2023-01-05. Estimated completion is 2024-03-20.
What interventions are being tested in trial NCT05470517?
The interventions under investigation include: Ceftriaxone (DRUG), Intra-peritoneal Fluid Aspiration (PROCEDURE).
Who is sponsoring clinical trial NCT05470517?
This trial is sponsored by Johns Hopkins All Children's Hospital, which has 24 total clinical trials registered on ClinicalTrials.gov.
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