Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05469373 · ClinicalTrials.gov registry record
ESIS in Pediatric DRE
A clinical trial of Epilepsy, sponsored by Sarah Katie Ihnen.
- Recruiting
- Registry status
- 86
- Enrollment target
- 1
- Study location
NCT05469373: Recruiting study of Epilepsy, sponsored by Sarah Katie Ihnen.
NCT05469373 is a study of Epilepsy that is actively recruiting participants, run by Sarah Katie Ihnen. The registered enrollment target is 86 participants, below the 952-participant average among 160 other Epilepsy trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05469373, a study of Epilepsy, is actively recruiting participants, sponsored by Sarah Katie Ihnen.
- RECRUITING
- Registry status
- 86 participants
- Enrollment target
- 1
- Study location
Study Summary
The main reason for this research study is to gain information about how the brain makes seizures by causing seizures using very small amounts of current, or electrical stimulation. Using small amounts of current to cause seizures (or stimulate) is not new at CCHMC - it is part of routine clinical practice for some patients at some electrodes. This study differs from routine clinical care in that all study patients will undergo electrical stimulation in all or nearly all electrode contacts. The study team is doing this because there is promising data in adult patients that stimulating comprehensively (targeting all or nearly all of the electrode contacts) helps define the seizure network. Defining the seizure network in turn helps the medical team plan surgery. So far, there is not as much published data on seizure stimulation for pediatric patients. This research study thus has the potential both to help individual patients (by providing specific information about your seizure networks) and to help pediatric patients with epilepsy in general (by increasing our understanding of stimulated seizures in children, teenagers and young adults).
Primary Outcome
Evaluate the safety of ESIS in pediatric DRE patients.
Conditions Studied
Study Locations (1)
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 86 participants |
| Start Date | 2022-02-17 |
| Est. Completion | 2027-12-31 |
What NCT05469373 shows while recruiting
NCT05469373 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 86 participants, a relatively small participant target, below the 952-participant average among 160 other Epilepsy trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Epilepsy appearing as the primary indexed condition, and to 0 interventions.
NCT05469373 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT05469373 about?
NCT05469373 is a clinical study titled "ESIS in Pediatric DRE". The main reason for this research study is to gain information about how the brain makes seizures by causing seizures using very small amounts of current, or electrical stimulation. Using small amounts of current to cause seizures (or stimulate) is not new at CCHMC - it is part of routine clinical p...
What is the current status of trial NCT05469373?
This trial is currently recruiting. The enrollment target is 86 participants. The study started on 2022-02-17. Estimated completion is 2027-12-31.
What conditions does trial NCT05469373 study?
This clinical trial studies the following conditions: Epilepsy.
Who is sponsoring clinical trial NCT05469373?
This trial is sponsored by Sarah Katie Ihnen, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05469373 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Epilepsy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05469373's enrollment target sits among peer trials
86 64th of 160 higher than 97 of 160 other Epilepsy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Epilepsy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes
RECRUITING
-
Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up
RECRUITING
-
SeizEAR Safety Study
RECRUITING · NA
-
Physiological-based Pharmacokinetics Approach to Medication Exposure During Pregnancy and Breastfeeding
RECRUITING
-
Tumor Related Epilepsy
RECRUITING
-
Study to Evaluate the Relative Bioavailability of a New Formulation of NPT 2042 Soft-Gelatin Capsules Compared to the Original Formulation of NPT 2042
RECRUITING · Phase 1
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01639508 · 86 participants · Phase 2
Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity
- NCT03519269 · 86 participants · NA
Navio Robotic Versus Conventional Total Knee Arthroplasty
- NCT04132999 · 86 participants · NA
PAP for Children With DS and OSAS
- NCT04545957 · 86 participants · NA
Jump: MR Simulation For Radiation Therapy Master Protocol
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI