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NCT05469113 · ClinicalTrials.gov registry record · Phase 1

A Study of Effects of Selpercatinib (LY3527723) on Repaglinide in Healthy Participants

A Phase 1 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 1
Development phase
16
Enrollment target

NCT05469113: Completed Phase 1 study, sponsored by Eli Lilly and Company.

NCT05469113 is a Phase 1 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05469113, a Phase 1 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 1
Development phase
16 participants
Enrollment target

Study Summary

The main purpose of this study is to assess the effect of selpercatinib on how fast repaglinide gets into the blood stream and how long it takes the body to remove it when administered in healthy participants. Information about safety and tolerability will be collected. The study will last up to 12 days.

Interventions

  • DRUG Selpercatinib
  • DRUG Repaglinide

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2019-01-29
Est. Completion 2019-03-05
Phase Phase 1
Eli Lilly and Company

1,341 total trials

What the finished NCT05469113 record still lists

NCT05469113 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).

The record links to 0 conditions, and to 2 interventions - of which Selpercatinib is the first listed.

NCT05469113 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05469113 about?

NCT05469113 is a clinical study titled "A Study of Effects of Selpercatinib (LY3527723) on Repaglinide in Healthy Participants". The main purpose of this study is to assess the effect of selpercatinib on how fast repaglinide gets into the blood stream and how long it takes the body to remove it when administered in healthy participants. Information about safety and tolerability will be collected. The study will last up to 12 ...

What is the current status of trial NCT05469113?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2019-01-29. Estimated completion is 2019-03-05.

What interventions are being tested in trial NCT05469113?

The interventions under investigation include: Selpercatinib (DRUG), Repaglinide (DRUG).

Who is sponsoring clinical trial NCT05469113?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05469113's enrollment target sits among peer trials

16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05469113, the US trial registry maintained by the National Library of Medicine. NCT05469113 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.