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NCT05460507 · ClinicalTrials.gov registry record · Phase 1

Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment

A Phase 1 study of Glioma, sponsored by Plus Therapeutics.

Recruiting
Registry status
Phase 1
Development phase
40
Enrollment target
1
Study location

NCT05460507 is a Phase 1 study of Glioma that is actively recruiting participants, run by Plus Therapeutics. The registered enrollment target is 40 participants, below the 210-participant average among 87 other Glioma trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05460507, a Phase 1 study of Glioma, is actively recruiting participants, sponsored by Plus Therapeutics.

RECRUITING
Registry status
Phase 1
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

This is an open-label, multicenter, Phase 1 study to establish the safety and efficacy/tolerability of a single dose of 186RNL by the intraventricular route (via intraventricular catheter) for recurrence glioma in patients who received a prior treatment of 186RNL.

Conditions Studied

Interventions

  • DRUG Retreatment Rhenium Liposome

Study Locations (1)

Texas

  • The Cancer Therapy and Research Center at UTHSCSA - San Antonio

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2024-12-12
Est. Completion 2028-03-01
Phase Phase 1

Sponsor

Plus Therapeutics

4 total trials

What the Registry Record Tells You About NCT05460507

The ClinicalTrials.gov registry entry for NCT05460507 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 210-participant average among 87 other Glioma trials with a reported enrollment target (81% lower). The listed sponsor is Plus Therapeutics, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Glioma appearing as the primary indexed condition, and to 1 intervention - of which Retreatment Rhenium Liposome is the first listed.

NCT05460507 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT05460507 about?

NCT05460507 is a clinical study titled "Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment". This is an open-label, multicenter, Phase 1 study to establish the safety and efficacy/tolerability of a single dose of 186RNL by the intraventricular route (via intraventricular catheter) for recurrence glioma in patients who received a prior treatment of 186RNL.

What is the current status of trial NCT05460507?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2024-12-12. Estimated completion is 2028-03-01.

What conditions does trial NCT05460507 study?

This clinical trial studies the following conditions: Glioma.

What interventions are being tested in trial NCT05460507?

The interventions under investigation include: Retreatment Rhenium Liposome (DRUG).

Who is sponsoring clinical trial NCT05460507?

This trial is sponsored by Plus Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05460507 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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