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NCT05458375 · ClinicalTrials.gov registry record · Early Phase 1
Vaginal Estradiol Use in Pessary Care
A Early Phase 1 study, sponsored by University of South Florida.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 11
- Enrollment target
NCT05458375: Clinical Trial Early Phase 1 study, sponsored by University of South Florida.
NCT05458375 is a Early Phase 1 study that was terminated before completion, run by University of South Florida. The registered enrollment target is 11 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (79% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05458375, a Early Phase 1 study, was terminated before completion, sponsored by University of South Florida.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 11 participants
- Enrollment target
Study Summary
The primary outcome of this study compare the rate of pessary discontinuation at 6 months post-pessary fitting in women using vaginal estradiol versus those not using vaginal estradiol.
Primary Outcome
To compare the rate of pessary discontinuation at 6 months post-pessary fitting in estrogen group and no intervention group
Interventions
- DRUG Estradiol vaginal cream
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2022-12-29 |
| Est. Completion | 2023-04-26 |
| Phase | Early Phase 1 |
Why NCT05458375 stopped before completion
NCT05458375 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (79% lower).
The record links to 0 conditions, and to 1 intervention - of which Estradiol vaginal cream is the first listed.
NCT05458375 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05458375 about?
NCT05458375 is a clinical study titled "Vaginal Estradiol Use in Pessary Care". The primary outcome of this study compare the rate of pessary discontinuation at 6 months post-pessary fitting in women using vaginal estradiol versus those not using vaginal estradiol.
What is the current status of trial NCT05458375?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 11 participants. The study started on 2022-12-29. Estimated completion is 2023-04-26.
What interventions are being tested in trial NCT05458375?
The interventions under investigation include: Estradiol vaginal cream (DRUG).
Who is sponsoring clinical trial NCT05458375?
This trial is sponsored by University of South Florida, which has 252 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05458375's enrollment target sits among peer trials
11 1600th of 2000 higher than 373 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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