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NCT05448040 · ClinicalTrials.gov registry record · NA
Clinical and Histological Assessment of Free Gingival Graft or Collagen Matrix for Socket Sealing After Bone Grafting
A NA study of Socket Sealing and Free Gingival Graft, sponsored by Universidade Salgado de Oliveira.
- Completed
- Registry status
- NA
- Development phase
- 18
- Enrollment target
- 1
- Study location
NCT05448040: Completed NA study of Socket Sealing and Free Gingival Graft, sponsored by Universidade Salgado de Oliveira.
NCT05448040 is a NA study of Socket Sealing and Free Gingival Graft that has completed, run by Universidade Salgado de Oliveira. The registered enrollment target is 18 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05448040, a NA study of Socket Sealing and Free Gingival Graft, has completed, sponsored by Universidade Salgado de Oliveira.
- COMPLETED
- Registry status
- NA
- Development phase
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study was to compare, clinical and histologically, the use of the suine collagen matrix (Mucograft Seal \[MS\], Geisthlich®) and the free gingival graft (FGG) for the alveolar sealing after inserted bone graft biomaterial. It was included 18 patients with tooth referred to extraction (maxilar incisives, canines, or pre-molars) which were randomly divided in 2 groups, according to the material for alveolus sealing: control (FGG) and test (MS). After the minimally traumatic extraction, all the alveoli were filled with bovine mineral matrix (Bio-Oss®), and the material for alveolar sealing were positioned and stabilized with sutures. The follow-up (clinical and photographic) happened on the immediate post-operatory period, and with 3, 7, 15, 30, 60, 90, and 120 days. After 120 days, before implant placement, tissues samples were obtained with a 3.5mm punch scalpel for histological analysis. Qualitative information related to the patient's perception considering the treatment were collected.
Primary Outcome
Socket preservation with xenograft biomaterial and another one to seal it (FGG or collagen membrane). Radiographic analysis - PA (periapical x-rays) comparing groups and periods of the follow-up. It was performed descriptive comparative analysis. Clinical evaluation - bleeding on probing (dichotomic analysis), ISQ (torque achieved - Osstell), qualitative analysis (questionnaire with 8 questions), and subjective appraisal of the soft tissue healing (according to the period of evaluation).
Conditions Studied
Interventions
- PROCEDURE Socket preservation
Study Locations (1)
Michigan
- UM - POM Dpt - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2018-02-01 |
| Est. Completion | 2021-11-30 |
| Phase | NA |
What the finished NCT05448040 record still lists
NCT05448040 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 3 conditions, with Socket Sealing appearing as the primary indexed condition, and to 1 intervention - of which Socket preservation is the first listed.
NCT05448040 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT05448040 about?
NCT05448040 is a clinical study titled "Clinical and Histological Assessment of Free Gingival Graft or Collagen Matrix for Socket Sealing After Bone Grafting". The goal of this study was to compare, clinical and histologically, the use of the suine collagen matrix (Mucograft Seal \[MS\], Geisthlich®) and the free gingival graft (FGG) for the alveolar sealing after inserted bone graft biomaterial. It was included 18 patients with tooth referred to extractio...
What is the current status of trial NCT05448040?
This trial is currently completed. It is a NA study. The enrollment target is 18 participants. The study started on 2018-02-01. Estimated completion is 2021-11-30.
What conditions does trial NCT05448040 study?
This clinical trial studies the following conditions: Socket Sealing, Free Gingival Graft, Collagen Membrane.
What interventions are being tested in trial NCT05448040?
The interventions under investigation include: Socket preservation (PROCEDURE).
Who is sponsoring clinical trial NCT05448040?
This trial is sponsored by Universidade Salgado de Oliveira, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05448040 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05448040's enrollment target sits among peer trials
18 1863rd of 2000 higher than 130 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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