Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05447650 · ClinicalTrials.gov registry record · NA

Microcurrent Stimulation Therapy for Nonexudative Age-related Macular Degeneration (i-SIGHT)

A NA study of Age-related Macular Degeneration and Dry Age-Related Macular Degeneration, sponsored by i-Lumen Scientific.

Completed
Registry status
NA
Development phase
95
Enrollment target
10
Study locations

NCT05447650: Completed NA study of Age-related Macular Degeneration and Dry Age-Related Macular Degeneration, sponsored by i-Lumen Scientific.

NCT05447650 is a NA study of Age-related Macular Degeneration and Dry Age-Related Macular Degeneration that has completed, run by i-Lumen Scientific. The registered enrollment target is 95 participants, below the 1,506-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (94% lower). The trial reports 10 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05447650, a NA study of Age-related Macular Degeneration and Dry Age-Related Macular Degeneration, has completed, sponsored by i-Lumen Scientific.

COMPLETED
Registry status
NA
Development phase
95 participants
Enrollment target
10
Study locations

Study Summary

Evaluate the safety and efficacy of transpalpebral microcurrent stimulation (MCS) therapy for patients with nonexudative (dry) age-related macular degeneration (AMD).

Primary Outcome

Incidence of device- and/or treatment-related serious adverse events (SAEs) and/or serious adverse device effects (SADE) at any point during the study

Conditions Studied

Age-related Macular Degeneration Dry Age-Related Macular Degeneration Non-exudative Age-related Macular Degeneration

Interventions

  • DEVICE i-Lumen(TM) AMD
  • DEVICE i-Lumen(TM) AMD Sham

Study Locations (10)

Texas

  • Austin Research Center for Retina - Austin
  • Retina Consultants of Texas - Bellaire
  • Star Retina - Burleson
  • Texas Retina Associates - Fort Worth

Pennsylvania

  • Cumberland Valley Retina Consultants - Chambersburg
  • Erie Retina Research, LLC - Erie

Arizona

  • Associated Retina Consultants - Phoenix

California

  • Bay Area Retina Associates - Walnut Creek

Illinois

  • University Retina and Macula Associates, PC - Lemont

Tennessee

  • Charles Retina Institute - Germantown

Trial Details

FieldValue
Enrollment Target 95 participants
Start Date 2022-04-12
Est. Completion 2025-06-15
Phase NA
i-Lumen Scientific

1 total trials

What the finished NCT05447650 record still lists

NCT05447650 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 95 participants, a relatively small participant target, below the 1,506-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (94% lower).

The record links to 3 conditions, with Age-related Macular Degeneration appearing as the primary indexed condition, and to 2 interventions - of which i-Lumen(TM) AMD is the first listed.

NCT05447650 lists 10 locations in 6 states (Texas, Pennsylvania, Arizona).

Frequently Asked Questions

What is clinical trial NCT05447650 about?

NCT05447650 is a clinical study titled "Microcurrent Stimulation Therapy for Nonexudative Age-related Macular Degeneration (i-SIGHT)". Evaluate the safety and efficacy of transpalpebral microcurrent stimulation (MCS) therapy for patients with nonexudative (dry) age-related macular degeneration (AMD).

What is the current status of trial NCT05447650?

This trial is currently completed. It is a NA study. The enrollment target is 95 participants. The study started on 2022-04-12. Estimated completion is 2025-06-15.

What conditions does trial NCT05447650 study?

This clinical trial studies the following conditions: Age-related Macular Degeneration, Dry Age-Related Macular Degeneration, Non-exudative Age-related Macular Degeneration.

What interventions are being tested in trial NCT05447650?

The interventions under investigation include: i-Lumen(TM) AMD (DEVICE), i-Lumen(TM) AMD Sham (DEVICE).

Who is sponsoring clinical trial NCT05447650?

This trial is sponsored by i-Lumen Scientific, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05447650 being conducted?

This trial has 10 study locations across Arizona, California, Illinois, Pennsylvania, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Age-related Macular Degeneration

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05447650's enrollment target sits among peer trials

95 34th of 74 higher than 41 of 74 other Age-related Macular Degeneration trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Age-related Macular Degeneration trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03339128 · 95 participants · Phase 2

    Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children

  • NCT03509961 · 95 participants · Phase 2

    The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL

  • NCT03694756 · 95 participants · NA

    TMEM-MRI: A Pilot Feasibility Study of MRI for Imaging of TMEM in Patients With Operable Breast Cancer

  • NCT04206215 · 95 participants · NA

    Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Related registry views

Source: ClinicalTrials.gov NCT05447650, the US trial registry maintained by the National Library of Medicine. NCT05447650 (small enrollment · multi site footprint · completed) retrieved and formatted by PlainTrial, see methodology.