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NCT05445557 · ClinicalTrials.gov registry record · Phase 2

Evaluation of Safety and Efficacy of RZL-012 in Subjects Seeking Fat Reduction in the Flanks

A Phase 2 study, sponsored by Raziel Therapeutics.

Completed
Registry status
Phase 2
Development phase
12
Enrollment target

NCT05445557: Completed Phase 2 study, sponsored by Raziel Therapeutics.

NCT05445557 is a Phase 2 study that has completed, run by Raziel Therapeutics. The registered enrollment target is 12 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05445557, a Phase 2 study, has completed, sponsored by Raziel Therapeutics.

COMPLETED
Registry status
Phase 2
Development phase
12 participants
Enrollment target

Study Summary

A total of 12 subjects will be injected with RZL-012 and placebo. Each of the subject's flanks will be randomized for each of the treatment. A total of 24 flanks will be randomized in the double blind phase. They will be monitored for safety and efficacy for 12 weeks. After codes opening, a second treatment cycle on the previously untreated contralateral flank will be done. Subjects will be monitored for safety and efficacy for additional 12 weeks.

Primary Outcome

Safety

Interventions

  • DRUG Placebo
  • DRUG RZL-012

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2022-03-10
Est. Completion 2022-11-10
Phase Phase 2
Raziel Therapeutics

9 total trials

What the finished NCT05445557 record still lists

NCT05445557 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT05445557 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05445557 about?

NCT05445557 is a clinical study titled "Evaluation of Safety and Efficacy of RZL-012 in Subjects Seeking Fat Reduction in the Flanks". A total of 12 subjects will be injected with RZL-012 and placebo. Each of the subject's flanks will be randomized for each of the treatment. A total of 24 flanks will be randomized in the double blind phase. They will be monitored for safety and efficacy for 12 weeks. After codes opening, a second t...

What is the current status of trial NCT05445557?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2022-03-10. Estimated completion is 2022-11-10.

What interventions are being tested in trial NCT05445557?

The interventions under investigation include: Placebo (DRUG), RZL-012 (DRUG).

Who is sponsoring clinical trial NCT05445557?

This trial is sponsored by Raziel Therapeutics, which has 9 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05445557's enrollment target sits among peer trials

12 1948th of 2000 higher than 34 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05445557, the US trial registry maintained by the National Library of Medicine. NCT05445557 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.