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NCT05436600 · ClinicalTrials.gov registry record · NA
Asymptomatic Carotid Stenosis and Mobility Function With Exercise Intervention
A NA study of Asymptomatic Carotid Stenosis (50-69%) and Mobility Impairment, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT05436600: Recruiting NA study of Asymptomatic Carotid Stenosis (50-69%) and Mobility Impairment, sponsored by VA Office of Research and Development.
NCT05436600 is a NA study of Asymptomatic Carotid Stenosis (50-69%) and Mobility Impairment that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05436600, a NA study of Asymptomatic Carotid Stenosis (50-69%) and Mobility Impairment, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Moderate (50-69%) asymptomatic carotid artery stenosis (ACAS) is an important and under-appreciated contributor to balance and mobility dysfunction. This is significant because declines in balance and mobility are a significant predictor of falls, disability, loss of independence, and death in older adults. Further, falls and fall-related injuries in older adults cost approximately 50 billion dollars annually in the United States, and are the leading cause of adverse events reported by the Veterans Health Administration. This proposal seeks to: 1) investigate the impact of a supervised aerobic and challenging balance exercise program on balance and mobility function in patients with moderate ACAS; and 2) elucidate whether these changes are related to changes in cerebral perfusion. With 830,000 Veterans estimated to have moderate ACAS and at risk for balance and mobility dysfunction and increased falls, the findings from this study could have significant impacts on the clinical management, quality of life, and functional independence of Veterans with moderate ACAS.
Primary Outcome
The Mini BESTest is a reliable and valid measure of balance and mobility that is sensitive to changes in individuals with balance dysfunction, and has age-related normative values. It will be the primary outcome measure to evaluate changes in balance and mobility following exercise intervention. The Mini BESTest includes fourteen items that evaluate the following: anticipatory postural adjustments, reactive postural control, sensory orientation, and dynamic gait.
Conditions Studied
Interventions
- OTHER Exercise Intervention
Study Locations (1)
Maryland
- Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2022-10-01 |
| Est. Completion | 2028-06-01 |
| Phase | NA |
What NCT05436600 shows while recruiting
NCT05436600 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 2 conditions, with Asymptomatic Carotid Stenosis (50-69%) appearing as the primary indexed condition, and to 1 intervention - of which Exercise Intervention is the first listed.
NCT05436600 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05436600 about?
NCT05436600 is a clinical study titled "Asymptomatic Carotid Stenosis and Mobility Function With Exercise Intervention". Moderate (50-69%) asymptomatic carotid artery stenosis (ACAS) is an important and under-appreciated contributor to balance and mobility dysfunction. This is significant because declines in balance and mobility are a significant predictor of falls, disability, loss of independence, and death in older...
What is the current status of trial NCT05436600?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2022-10-01. Estimated completion is 2028-06-01.
What conditions does trial NCT05436600 study?
This clinical trial studies the following conditions: Asymptomatic Carotid Stenosis (50-69%), Mobility Impairment.
What interventions are being tested in trial NCT05436600?
The interventions under investigation include: Exercise Intervention (OTHER).
Who is sponsoring clinical trial NCT05436600?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05436600 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05436600's enrollment target sits among peer trials
50 1280th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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