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NCT05433961 · ClinicalTrials.gov registry record · Phase 1
Functional and Structural Assessment of Endobronchial Valve Recipients Using Dynamic Hyperpolarized Xenon-129 MRI
A Phase 1 study, sponsored by Xemed.
- Terminated
- Registry status
- Phase 1
- Development phase
- 27
- Enrollment target
NCT05433961 is a Phase 1 study that was terminated before completion, run by Xemed. The registered enrollment target is 27 participants.
The verdict
NCT05433961, a Phase 1 study, was terminated before completion, sponsored by Xemed.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 27 participants
- Enrollment target
Study Summary
This study proposes to use hyperpolarized xenon-129 Magnetic Resonance Imaging (MRI) to study lung function of COPD patients who will receive endobronchial valve (EBV) therapy as part of their clinical standard-of-care. Once inhaled, HP xenon can provide information to imagers regarding functionality across specific regions of the lungs through the assessment of the replacement of air during the normal breathing cycle, how much oxygen is in the airspaces, and if the normal spongy tissue structure has been compromised by lung disease. Pre- (baseline) and post-EBV (follow-up) lung function imaging with HPXe will potentially lead to be better understand disease progression and treatment mechanism.
Interventions
- DRUG MagniXene Hyperpolarized Xenon MRI
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2023-10-20 |
| Est. Completion | 2025-09-11 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05433961
The ClinicalTrials.gov registry entry for NCT05433961 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 27 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Xemed, which has 5 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which MagniXene Hyperpolarized Xenon MRI is the first listed.
NCT05433961 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05433961 about?
NCT05433961 is a clinical study titled "Functional and Structural Assessment of Endobronchial Valve Recipients Using Dynamic Hyperpolarized Xenon-129 MRI". This study proposes to use hyperpolarized xenon-129 Magnetic Resonance Imaging (MRI) to study lung function of COPD patients who will receive endobronchial valve (EBV) therapy as part of their clinical standard-of-care. Once inhaled, HP xenon can provide information to imagers regarding functionalit...
What is the current status of trial NCT05433961?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2023-10-20. Estimated completion is 2025-09-11.
What interventions are being tested in trial NCT05433961?
The interventions under investigation include: MagniXene Hyperpolarized Xenon MRI (DRUG).
Who is sponsoring clinical trial NCT05433961?
This trial is sponsored by Xemed, which has 5 total clinical trials registered on ClinicalTrials.gov.
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