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NCT05422742 · ClinicalTrials.gov registry record · NA
Influence of SRP With MM on the Composition and Functional Characteristics of Subgingival Microbiome Communities
A NA study of Periodontitis, sponsored by West Virginia University.
- Active
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT05422742: Active NA study of Periodontitis, sponsored by West Virginia University.
NCT05422742 is a NA study of Periodontitis that is active but no longer recruiting, run by West Virginia University. The registered enrollment target is 50 participants, below the 110-participant average among 11 other Periodontitis trials with a reported enrollment target (55% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05422742, a NA study of Periodontitis, is active but no longer recruiting, sponsored by West Virginia University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to characterize the effect of minocycline microspheres (MM) administered as an adjunct to scaling and rooting planning (SRP) on the subgingival community composition and metatranscriptome functional profile, in comparison to a group treated with SRP only and to periodontally-healthy subjects.
Primary Outcome
Change in Clinical Attachment Loss which is a routine clinical measure of periodontal health (measured in mm) from baseline to 2 months post procedure
Conditions Studied
Interventions
- PROCEDURE SRP + MM
- PROCEDURE Scaling and Root Planing (SRP)
Study Locations (1)
West Virginia
- West Virginia University - Morgantown
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2021-10-15 |
| Est. Completion | 2025-12 |
| Phase | NA |
What the registry record for NCT05422742 still lists
NCT05422742 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 110-participant average among 11 other Periodontitis trials with a reported enrollment target (55% lower).
The record links to 1 condition, with Periodontitis appearing as the primary indexed condition, and to 2 interventions - of which SRP + MM is the first listed.
NCT05422742 reports a single indexed study location in West Virginia.
Frequently Asked Questions
What is clinical trial NCT05422742 about?
NCT05422742 is a clinical study titled "Influence of SRP With MM on the Composition and Functional Characteristics of Subgingival Microbiome Communities". The purpose of this study is to characterize the effect of minocycline microspheres (MM) administered as an adjunct to scaling and rooting planning (SRP) on the subgingival community composition and metatranscriptome functional profile, in comparison to a group treated with SRP only and to periodont...
What is the current status of trial NCT05422742?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2021-10-15. Estimated completion is 2025-12.
What conditions does trial NCT05422742 study?
This clinical trial studies the following conditions: Periodontitis.
What interventions are being tested in trial NCT05422742?
The interventions under investigation include: SRP + MM (PROCEDURE), Scaling and Root Planing (SRP) (PROCEDURE).
Who is sponsoring clinical trial NCT05422742?
This trial is sponsored by West Virginia University, which has 122 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05422742 being conducted?
This trial has 1 study location across West Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Periodontitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05422742's enrollment target sits among peer trials
50 9th of 11 higher than 3 of 11 other Periodontitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Periodontitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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