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ACTIVE NOT RECRUITING NA

Influence of SRP With MM on the Composition and Functional Characteristics of Subgingival Microbiome Communities

NCT05422742 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to characterize the effect of minocycline microspheres (MM) administered as an adjunct to scaling and rooting planning (SRP) on the subgingival community composition and metatranscriptome functional profile, in comparison to a group treated with SRP only and to periodontally-healthy subjects.

Conditions Studied

Interventions

  • PROCEDURE SRP + MM
  • PROCEDURE Scaling and Root Planing (SRP)

Study Locations (1)

West Virginia

  • West Virginia University — Morgantown

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2021-10-15
Est. Completion 2025-12
Phase NA

Sponsor

West Virginia University

93 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05422742

The ClinicalTrials.gov registry entry for NCT05422742 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is West Virginia University, which has 93 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Periodontitis appearing as the primary indexed condition, and to 2 interventions — of which SRP + MM is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05422742 reports 1 study location spanning 1 distinct geographic area — top geographies include West Virginia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05422742 about?

NCT05422742 is a clinical study titled "Influence of SRP With MM on the Composition and Functional Characteristics of Subgingival Microbiome Communities". The purpose of this study is to characterize the effect of minocycline microspheres (MM) administered as an adjunct to scaling and rooting planning (SRP) on the subgingival community composition and metatranscriptome functional profile, in comparison to a group treated with SRP only and to periodont...

What is the current status of trial NCT05422742?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2021-10-15. Estimated completion is 2025-12.

What conditions does trial NCT05422742 study?

This clinical trial studies the following conditions: Periodontitis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05422742?

The interventions under investigation include: SRP + MM (PROCEDURE), Scaling and Root Planing (SRP) (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05422742?

This trial is sponsored by West Virginia University, which has 93 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05422742 being conducted?

This trial has 1 study location across West Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial