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NCT05384769 · ClinicalTrials.gov registry record · NA
Feasibility of Cell-Free DNA Liquid Biopsy in Screening High-Risk Patients for Lung Cancer
A NA study of Lung Carcinoma, sponsored by City of Hope Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 108
- Enrollment target
- 1
- Study location
NCT05384769: Recruiting NA study of Lung Carcinoma, sponsored by City of Hope Medical Center.
NCT05384769 is a NA study of Lung Carcinoma that is actively recruiting participants, run by City of Hope Medical Center. The registered enrollment target is 108 participants, below the 5,041-participant average among 38 other Lung Carcinoma trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05384769, a NA study of Lung Carcinoma, is actively recruiting participants, sponsored by City of Hope Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 108 participants
- Enrollment target
- 1
- Study location
Study Summary
This clinical trial investigates how practical and doable (feasibility) cell-free deoxyribonucleic acid (DNA) liquid biopsy is in screening high-risk patients for lung cancer. Currently, a low dose computed tomography (CT) scan is used to screen for lung cancer, however, due to various factors, few high-risk patients are screened. Liquid biopsy utilizes technology that can detect small amounts of DNA shed by cancer cells and may be able to spot lung cancer at an earlier stage. If a positive result comes back from the liquid biopsy, a patient may be more willing to get a low dose CT (LDCT) scan, possibly confirming the biopsy's findings and thus leading to more early lung cancer detection.
Primary Outcome
The proportion of participants who agree to undergo lung cancer screening using liquid biopsy versus LDCT, with a feasibility threshold of at least 30% preferring liquid biopsy.
Conditions Studied
Interventions
- OTHER Survey Administration
- PROCEDURE Liquid Biopsy
- PROCEDURE Low Dose Computed Tomography of the Chest
Study Locations (1)
California
- City of Hope Medical Center - Duarte
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 108 participants |
| Start Date | 2022-07-29 |
| Est. Completion | 2029-01-28 |
| Phase | NA |
What NCT05384769 shows while recruiting
NCT05384769 is an interventional study that assigns participants to a tested intervention. The registered 108 participants enrollment target is mid-sized for trials with a published cap, below the 5,041-participant average among 38 other Lung Carcinoma trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Lung Carcinoma appearing as the primary indexed condition, and to 3 interventions - of which Survey Administration is the first listed.
NCT05384769 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05384769 about?
NCT05384769 is a clinical study titled "Feasibility of Cell-Free DNA Liquid Biopsy in Screening High-Risk Patients for Lung Cancer". This clinical trial investigates how practical and doable (feasibility) cell-free deoxyribonucleic acid (DNA) liquid biopsy is in screening high-risk patients for lung cancer. Currently, a low dose computed tomography (CT) scan is used to screen for lung cancer, however, due to various factors, few ...
What is the current status of trial NCT05384769?
This trial is currently recruiting. It is a NA study. The enrollment target is 108 participants. The study started on 2022-07-29. Estimated completion is 2029-01-28.
What conditions does trial NCT05384769 study?
This clinical trial studies the following conditions: Lung Carcinoma.
What interventions are being tested in trial NCT05384769?
The interventions under investigation include: Survey Administration (OTHER), Liquid Biopsy (PROCEDURE), Low Dose Computed Tomography of the Chest (PROCEDURE).
Who is sponsoring clinical trial NCT05384769?
This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05384769 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Lung Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05384769's enrollment target sits among peer trials
108 18th of 38 higher than 21 of 38 other Lung Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lung Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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