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NCT05379270 · ClinicalTrials.gov registry record · NA
Intergenerational Transmission of Low-calorie Sweeteners Via Breast Milk
A NA study, sponsored by George Washington University.
- Completed
- Registry status
- NA
- Development phase
- 82
- Enrollment target
NCT05379270: Completed NA study, sponsored by George Washington University.
NCT05379270 is a NA study that has completed, run by George Washington University. The registered enrollment target is 82 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05379270, a NA study, has completed, sponsored by George Washington University.
- COMPLETED
- Registry status
- NA
- Development phase
- 82 participants
- Enrollment target
Study Summary
This project aims to measure the widely consumed low-calorie sweeteners (LCS) sucralose and acesulfame-potassium, in maternal breast milk and plasma at pre-specified timepoints over 72 hours and in a single sample of infants' plasma. Sucralose and acesulfame-potassium concentrations will be measured using liquid chromatography-mass spectrometry (LC-MS). The data generated will inform the design of larger, longer-term, prospective studies needed to investigate clinically-relevant consequences of early life LCS exposure in humans.
Primary Outcome
Mean concentration of sucralose in breast milk collected from mothers measured immediately prior to ingestion of the diet beverage containing sucralose and acesulfame-potassium.
Interventions
- OTHER Diet soda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 82 participants |
| Start Date | 2022-02-28 |
| Est. Completion | 2022-12-02 |
| Phase | NA |
What the finished NCT05379270 record still lists
NCT05379270 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 82 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 1 intervention - of which Diet soda is the first listed.
NCT05379270 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05379270 about?
NCT05379270 is a clinical study titled "Intergenerational Transmission of Low-calorie Sweeteners Via Breast Milk". This project aims to measure the widely consumed low-calorie sweeteners (LCS) sucralose and acesulfame-potassium, in maternal breast milk and plasma at pre-specified timepoints over 72 hours and in a single sample of infants' plasma. Sucralose and acesulfame-potassium concentrations will be measured...
What is the current status of trial NCT05379270?
This trial is currently completed. It is a NA study. The enrollment target is 82 participants. The study started on 2022-02-28. Estimated completion is 2022-12-02.
What interventions are being tested in trial NCT05379270?
The interventions under investigation include: Diet soda (OTHER).
Who is sponsoring clinical trial NCT05379270?
This trial is sponsored by George Washington University, which has 133 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05379270's enrollment target sits among peer trials
82 990th of 2000 higher than 1,009 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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