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NCT05358886 · ClinicalTrials.gov registry record · Phase 3
A Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome
A Phase 3 study, sponsored by Tetra Discovery Partners.
- Completed
- Registry status
- Phase 3
- Development phase
- 171
- Enrollment target
NCT05358886: Completed Phase 3 study, sponsored by Tetra Discovery Partners.
NCT05358886 is a Phase 3 study that has completed, run by Tetra Discovery Partners. The registered enrollment target is 171 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05358886, a Phase 3 study, has completed, sponsored by Tetra Discovery Partners.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 171 participants
- Enrollment target
Study Summary
A Randomized, Double-blind, Placebo-controlled, Parallel Group Study of BPN14770 in Male Adults (Aged 18 to 45) with Fragile X Syndrome
Primary Outcome
National Institutes of Health Toolbox Cognitive Battery cognition crystallized composite score (NIH-TCB CCC), which is calculated from the Picture Vocabulary and Oral Reading domains.
Interventions
- DRUG Placebo
- DRUG BPN14770/ zatolmilast
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 171 participants |
| Start Date | 2022-11-01 |
| Est. Completion | 2025-07-18 |
| Phase | Phase 3 |
What the finished NCT05358886 record still lists
NCT05358886 is an interventional study that assigns participants to a tested intervention. The registered 171 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (78% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05358886 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05358886 about?
NCT05358886 is a clinical study titled "A Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome". A Randomized, Double-blind, Placebo-controlled, Parallel Group Study of BPN14770 in Male Adults (Aged 18 to 45) with Fragile X Syndrome
What is the current status of trial NCT05358886?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 171 participants. The study started on 2022-11-01. Estimated completion is 2025-07-18.
What interventions are being tested in trial NCT05358886?
The interventions under investigation include: Placebo (DRUG), BPN14770/ zatolmilast (DRUG).
Who is sponsoring clinical trial NCT05358886?
This trial is sponsored by Tetra Discovery Partners, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05358886's enrollment target sits among peer trials
171 1451st of 2000 higher than 548 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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