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NCT05345717 · ClinicalTrials.gov registry record · Phase 1

Novel Desensitization Kidney Transplantation

A Phase 1 study, sponsored by University of Chicago.

Completed
Registry status
Phase 1
Development phase
5
Enrollment target

NCT05345717: Completed Phase 1 study, sponsored by University of Chicago.

NCT05345717 is a Phase 1 study that has completed, run by University of Chicago. The registered enrollment target is 5 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05345717, a Phase 1 study, has completed, sponsored by University of Chicago.

COMPLETED
Registry status
Phase 1
Development phase
5 participants
Enrollment target

Study Summary

This proposal's objective is to determine whether belatacept, in conjunction with a proteasome inhibitor can be used to safely increase the likelihood of finding an acceptable donor for highly HLA sensitized kidney transplant candidates.

Primary Outcome

The likelihood of finding a suitable donor will calculated base on calculated Panel of Reactive Antibodies measured 1month after the therapy

Interventions

  • DRUG Belatacept Injection

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2022-05-01
Est. Completion 2025-09-12
Phase Phase 1
University of Chicago

796 total trials

What the finished NCT05345717 record still lists

NCT05345717 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 1 intervention - of which Belatacept Injection is the first listed.

NCT05345717 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05345717 about?

NCT05345717 is a clinical study titled "Novel Desensitization Kidney Transplantation". This proposal's objective is to determine whether belatacept, in conjunction with a proteasome inhibitor can be used to safely increase the likelihood of finding an acceptable donor for highly HLA sensitized kidney transplant candidates.

What is the current status of trial NCT05345717?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2022-05-01. Estimated completion is 2025-09-12.

What interventions are being tested in trial NCT05345717?

The interventions under investigation include: Belatacept Injection (DRUG).

Who is sponsoring clinical trial NCT05345717?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05345717's enrollment target sits among peer trials

5 1989th of 2000 higher than 6 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05345717, the US trial registry maintained by the National Library of Medicine. NCT05345717 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.